Polyethylene (PE) has recently gained attention as an advantageous support material in forward osmosis (FO) owing to its low structural parameters. A novel thin-film composite (TFC) membrane for FO was fabricated by introducing a tannic acid (TA)-Fe3+ interlayer on polydopamine (PDA)-modified PE via interfacial polymerization. The TA-Fe3+ influenced the diffusion of m-phenylenediamine, causing ...

Recent findings regarding nanofiltration (NF) have led to indications that it can be successfully used for separation of various biological solutions. As a novelty, this paper is the first investigate impact feed pretreatment process on NF membrane performance 1,3-propanediol (1,3-PD) fermentation broths. For purpose, prior process, was purified by microfiltration (MF) and ultrafiltration (UF) ...

In this work, polyamide (PA)/silica nanocomposite films prepared by dissolution method of composite mixing were investigated. The morphology of nanocomposite films were characterized using scanning electron microscope (SEM), reveals that nano silica powder were uniformly dispersed on PA silica nanocomposite film. Chemical composition of film was confirmed by Fourier transform infrared spectrosc...

Disclosed is an inhibitor of the expression of CTGF gene, which comprises a pyrrole-imidazole polyamide. The pyrrole-imidazole polyamide has an N-methylpyrrole unit (hereinafter, referred to as “Py”), an N-methylimidazole unit (hereinafter, referred to as “Im”) and a ϝ-aminobutanoic acid unit. In the pyrrole-imidazole polyamide, the region of the ϝ-aminobutanoic acid unit is folded to form an U...

High-performance polymeric membrane technology is rapidly developing worldwide with the introduction of new materials and processes. Considerable research efforts are being made to establish a polymer that can be used for ultrafiltration (UF) or nanofiltration (NF) applications. The development modified polyamide-66 its compatibility in wastewater essential elements quest advances improvements ...

In an effort to quantitate Py-Im polyamide concentrations in vivo, we synthesized the C-14 radioactively labeled compounds 1-3, and investigated their tumor localization in a subcutaneous xenograft model of prostate cancer (LNCaP). Tumor concentrations were compared with representative host tissues, and exhibited a certain degree of preferential localization to the xenograft. Compound accumulat...

The functional silica/polyamide-imide composite films were prepared via simple ultrasonic blending, after the silica nanoparticles were modified by cationic surfactant-cetyltrimethyl ammonium bromide (CTAB). The composite films were characterized by scanning electron microscope (SEM), thermo gravimetric analysis (TGA) and thermomechanical analysis (TMA). CTAB-modified silica nanoparticles were ...

The design of molecules that damage a selected DNA sequence provides a formidable opportunity for basic and applied biology. For example, such molecules offer new prospects for controlled manipulation of the genome. The conjugation of DNA-code reading molecules such as polyamides to reagents that induce DNA damages provides an approach to reach this goal. In this work, we showed that a bipyridi...

Aberrant overexpression of ERG induced by the TMPRSS2-ERG gene fusion is likely involved in the development of prostate cancer. Synthetic pyrrole-imidazole (PI) polyamides recognize and attach to the minor groove of DNA with high affinity and specificity. In the present study, we designed a PI polyamide targeting TMPRSS2-ERG translocation breakpoints and assessed its effect on human prostate ca...

Abstract An integrally skinned organic solvent-resistant membrane with asymmetric structure for solvent nanofiltration (OSN) application was developed via thermally induced phase separation (TIPS) of nanocomposite polyamide 6. The 6 contains intercalated silicate sheets, which could improve the mechanical properties resultant membrane, as well mitigate swelling after exposure in solvent. influe...