The Mn2+ and Mo6+ based metal-mercaptoacetate (metal-MA) hybrids were prepared by a simple acid–base titration method. metal-MA analysed FT-IR spectroscopy, UV–visible SEM, particle size analyser (PSA), XRD EDX. investigated to assess their catalytic activity for ring-opening polymerization (ROP) of ε-caprolactone (CL) in the absence an initiator at 160 °C N2 atmosphere varying catalyst concent...

The morphology and miscibility of semi-interpenetrating polymer networks (semi-IPN) prepared with poly(styrene-co-methacrylic acid) [P(S-co-MAA)] of different carboxylic acid contents and poly(epsilon-caprolactone) (PCL) have been studied by ESR spin-label method. The ESR spectra of spin-labeled PCL showed one motional component at any specific temperature. It indicated that the spin-labeled mo...

Multi-walled carbon nanotubes (MWNTs) have been successfully modified by polystyrene, poly( caprolactone), and their block copolymers by addition reaction of the alkoxyamine-terminated precursors. Polymer-modified MWNTs are easily dispersed in good solvents for the grafted polymer, such as toluene and THF. This observation has been confirmed by TEM analysis. The grafting ratio of polystyrene ch...

In Vitro and In Vivo Bactericidal Activities of Vancomycin Dispersed in Porous Biodegradable Poly(ε-Caprolactone) Microparticles Anne-Marie Le Ray, Hélène Gautier, Marie-Katel Laty, Guy Daculsi, Christian Merle, Cédric Jacqueline, Antoine Hamel, and Jocelyne Caillon* Centre de Recherche sur les Matériaux d’Intérêt Biologique, Equipe INSERM 99-03, UFR Odontologie, Laboratoire de Pharmacie Galéni...

Galway, Ireland Human Mesenchymal Stem Cells Adhere and Proliferate onto Films of Poly(ε-caprolactone) with Hydroxylic Functional Groups Hajar Seyednejad, Tina Vermonden, Natalja E. Fedorovich, Mies J. van Steenbergen, Wouter J. A. Dhert, Cornelus F. van Nostrum, Wim E. Hennink Corresponding author: [email protected] Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UI...

Magnetic nanoparticle systems can be divided into single-core nanoparticles (with only one magnetic core per particle) and magnetic multi-core nanoparticles (with several magnetic cores per particle). Here, we report multi-core nanoparticle synthesis based on a controlled precipitation process within a well-defined oil in water emulsion to trap the superparamagnetic iron oxide nanoparticles (SP...

The enzymatic ring-opening copolymerization of ε-caprolactone (ε-CL) and β-lactam by using Candida antarctica lipase B (CAL-B) as catalyst was studied. Variation of the feed ratios of 25:75, 50:50, and 75:25 of ε-CL/β-lactam was performed. The products contain poly(ε-CL-co-β-lactam) and the homopolymers of poly(ε-CL) and poly(β-lactam). The structure of the copolymers was determined by MALDI-To...

The effects of blend weight ratio and polyester block length of methoxy poly(ethylene glycol)-b-poly( d, l-lactide) (MPEG- b-PDLL)/methoxy poly(ethylene glycol)- b-poly(ϵ-caprolactone) (MPEG- b-PCL) blends on nanoparticle characteristics and drug release behaviors were evaluated. The blend nanoparticles were prepared by nanoprecipitation method for controlled release of a poorly water-soluble m...