Well-controlled poly(alpha-hydroxyacids) featuring pendant carboxylic acid groups were prepared under mild conditions via DMAP-catalyzed ROP of the O-carboxyanhydrides derived from glutamic and lactic acids.

Lactic acid is a valuable and fully degradable organic acid with promising applications in poly-lactic acid production (Taskila S and Ojamo, 2013 [1]). Despite their efficiency, the cost of the current lactic acid bio-processes is still an obstacle to this application (Miller et al., 2011 [2]). To ameliorate lactic acid producing strains, researchers are using mutations and metabolic engineerin...

poly (lactide-co-glycolide)/bioactive glass/hydroxyapatite (pbgha) and poly (lactide-co-glycolide)/ bioactive glass (pbg) nanocomposite coatings with bone. materials and methods: sol-gel derived 58s bioactive glass nanoparticles, 50/50 wt% poly (lactic acid)/poly (glycolic acid) and hydroxyapatite nanoparticles were used to prepare the coatings. the nanocomposite coatings were characterized by ...

BACKGROUND Lactic acid is the building block of poly-lactic acid (PLA), a biopolymer that could be set to replace petroleum-based plastics. To make lactic acid production cost-effective, the production process should be carried out at low pH, in low-nutrient media, and with a low-cost carbon source. Yeasts have been engineered to produce high levels of lactic acid at low pH from glucose but not...

Kinema, an ethnic fermented, non-salted and sticky soybean food is consumed in the eastern part of India. The stickiness is one of the best qualities of good kinema preferred by consumers, which is due to the production of poly-γ-glutamic acid (PGA). Average load of Bacillus in kinema was 10(7) cfu/g and of lactic acid bacteria was 10(3) cfu/g. Bacillus spp. were screened for PGA-production and...

Abstract PLA and its nanocomposite containing 3% chitosan nanoparticles (PLA-3CsNP) were studied to see how γ -irradiation affected their characteristics. Different doses of applied the investigated materials under inquiry (5–40 kGy) using 60 Co at ambient conditions. The irradiation characterized by FT-IR, GPC, mechanical tensile test, DSC, XRD, TGA in solid chloroform solutions. molecular wei...

Purpose: The purpose of this study is to compare the time-course changes in condylar long axis and skeletal stability after sagittal split ramus osteotomy (SSRO) with unsintered hydroxyapatite (u-HA) / poly-L-lactic acid (PLLA) plate, PLLA plate versus titanium plate. Patients and Methods: Of 60 Japanese patients diagnosed of mandibular prognathism, 20 underwent SSRO with u-HA/PLLA plate system...

The superlative mechanical properties of graphene-based materials make them the ideal filler materials for polymer composites reinforcement. Two types of graphene-based materials, graphene nanoplatelets (xGnP) and reduced graphene oxide (rGO), were used as nanofiller in poly(lactic acid) (PLA) polymer matrix, as well as plasticized PLA. The addition of rGO into PLA or plasticized PLA substantia...

Background Since poly(L-lactic acid) (PLLA) shows great biocompatibility as well as biodegradability [1] and bacterial cellulose (BC) is a high purity biomaterial with unique structural and mechanical properties, composed of cellulose and water [2,3], both are biopolymers with great potential for biomedical applications. This work had the purpose of producing biocomposites with properties that ...

the purpose of this study was to investigate the effect of additives, poly(ethylene glycol) (peg) 1450, poloxamer 407, polyvinyl alcohol (pva) and sodium chloride in order to improve physico-chemical characteristics, encapsulation efficiency and in vitro release of bovine serum albumin, form poly(d,l-lactic-co-glycolic acid) (plga) microparticles prepared by the w/o/w solvent evaporation method...