This work introduces a novel MILP formulation for reactive scheduling of multiproduct batch plants to optimally generate updated schedules due to the occurrence of unforeseen events. It can also be used to improve a non-optimal production schedule before it is executed. The approach is based on a continuous-time problem representation that takes into account the schedule in progress, the update...

Today, memorable experiences are the leading economic value proposition that tourism industry holds. This article aims to theoretically investigate relationship between senses, emotions and memories in tourist experience present a conceptual model about establishment. Based on literature review, we concluded construction of is result multi-sensory stimuli perception, positive emotions, high emo...

Background: Hepatitis C virus (HCV) infection is the most common transfusion transmitted disease in poly-transfused patients worldwide. In this study we aimed to evaluate the effects of pegylated interferon alfa-2a (PEG-IFN A-2a) in reducing serum ALT and eradicating serum hepatitis C virus (HCV) RNA in HCV infected polytransfused thalassemic patients. Materials and Methods: A cohort of 51 HCV-...

Streams of user-generated content in social media exhibit patterns of collective attention across diverse topics, with temporal structures determined both by exogenous factors and endogenous factors. Teasing apart different topics and resolving their individual, concurrent, activity timelines is a key challenge in extracting knowledge from microblog streams. Facing this challenge requires the u...

Steel production is a complex process and finding coherent and effective schedules for the wide variety of production steps, in a dynamic environment, is a challenging task. In this paper we propose a multi-agent architecture for integrated dynamic scheduling of the hot strip mill and the continuous caster. The scheduling systems of these processes have very different objectives and constraints...

Practical scheduling usually has to react to many unpredictable events and uncertainties in the production environment. Although often possible in theory, it is undesirable to reschedule from scratch in such cases. Since the surrounding organization will be prepared for the predicted schedule it is important to change only those features of the schedule that are necessary. We show how on one si...

The strong increase of the contribution of renewable sources (wind, solar) to the power generation portfolio has increased uncertainty in the operation of the grid and has motivated efforts in demand-side management. Of particular interest is the demand response (DR) operation of large industrial electricity consumers, which is encouraged via (real-)time-varying electricity pricing schemes. For...