Aloe vera plant (A. vulgari and A. barbadensis) has being used traditionally as a medicinal plant for centuries. Gel from the inner central zone of the leaves and latex from pericyclic cells are used for medicinal purposes. The present study was conducted to elucidate the beneficial effects of Aloe vera juice on the platelet aggregation in cerebral microvessels of mice. Male mice were injected ...

Objective- This study aimed to evaluate the feasibility of using platelet rich fibrin membrane as a novel on-lay patching biomaterial in canine esophagotomy and its effects on esophageal wound healing. Design- Experimental study. Animals- Eight adult mixed breed dogs of both sexes equally allocated to control and treatment groups.<b...

The present study was designed to evaluate the effects of platelet growth factors and periosteal mesenchymal stem cells on bone healing process, radiographically. Forty male White New Zealand rabbits in five equal groups were used in this study. A 2 mm full thickness bone defect was made in left radial bone of each animal. In group A (control) the defect was left with no medical intervention. I...

A series of novel 2-aminopyrimidine and 2-Substituted-4,6-diaminopyrimidine derivatives have been synthesized and their anti platelet aggregation activities were assessed against ADP and arachidonic acid- induced platelet aggregation in human plasma using light transmission aggregometry. None of the compounds showed satisfactory activity against the aggregation induced by ADP. However, satisfac...

Dithranol is a potent agent in treating psoriasis but its adverse effects on intact skin have limited its usage. There are many proposed mediators for its adverse effects including prostaglandins, histamine, platelet activating factor and free radicals. In this study we examined the effect of different agents (diazepam, terfenadine, indomethacin and garlic extract) on dithranol-induced skin dam...

Platelet transfusions can be lifesaving for neonates with thrombocytopenic hemorrhage. However, multiple themselves convey risks and hazards. We cared a preterm neonate severe/prolonged acquired thrombocytopenia who received 61 platelet transfusions. Her counts stabilized, further were not needed, following three escalating doses of romiplostim.

Introduction: Homeopathy can be applied to treat various diseases and conditions such as cancer, allergy, mood disorders, headache and pain. This case showed that homeopathic medicine can be a treatment modality for idiopathic thrombocytopenic purpura (ITP), an autoimmune-mediated hematologic disorder. Case Presentation: The patient was a 5.5–year-old child wi...