objective studies on the effect of various antiepileptic drugs on serum lipids show contradictory results. we aimed to find the effect of phenobarbital and sodium valproate monotherapy on serum lipid profile and liver function tests in epileptic children. materials & methods this cohort study was conducted in amirkola children hospital. one hundred and ten children with epilepsy were included i...

Evidence of the role of ANGPTL3, a liver-secreted glycoprotein, in serum lipid turnover, led us to hypothesize that this protein may be involved in modification of the lipid profile induced by exercise-training. Given the lack of data regarding this issue, the main goal of the present study was to investigate the effects of regular participation in a recreational physical activity program on se...

OBJECTIVE The impact of prolonged subclinical hyperthyroidism on glucose and lipid metabolism is unclear. Therefore, we evaluated glucose and lipid metabolism in patients with differentiated thyroid carcinoma (DTC) on TSH suppressive thyroxine therapy as a model for subclinical hyperthyroidism and investigated whether restoration to euthyroidism affects metabolism. DESIGN We performed a prosp...

BACKGROUND Alterations in serum lipids have long been associated with cancer as lipids play an important role in maintenance of cell integrity. AIMS To evaluate alterations in plasma lipid profile in oral cancer patients, to compare and correlate the serum lipid profile in different grades of carcinoma and to evaluate the correlation of serum lipid profile between the tobacco habituates and n...

OBJECTIVE To examine the association between breast-feeding and blood pressure, anthropometry and plasma lipid profile in both adolescence and young adulthood. DESIGN Longitudinal study of biological and behavioural risk factors for CVD. SETTING The Young Hearts Project, Northern Ireland. SUBJECTS Schoolchildren aged 12 years and 15 years who participated in a cross-sectional study of lif...

In order to find a prophylactic supplementation for individuals who are at risk of exposure to ionizing radiation, we attempted to evaluate the effect of Vitamin E (Vit-E), a biological free radical scavenger, on restoration of hepatic lipid peroxidation (LPO) and lipid profile (LP) changes induced by sublethal g- radiation in BALB/c mice. The concentrations of cholesterol and phospholipid were...

BACKGROUND We examined the effect of the oral SIRT1 activator SRT2104 on cardiovascular function in otherwise healthy cigarette smokers. METHODS AND RESULTS Twenty-four otherwise healthy cigarette smokers participated in a randomized double-blind, placebo-controlled crossover trial and received 28 days of oral SRT2104 (2.0 g/day) or matched placebo. Plasma SRT2104 concentrations, serum lipid ...

background: changes in the lipid profile have been suggested as a risk factor for developing ischemic stroke. their role in intra-cerebral hemorrhage, however, is not clear. the present study was designed to evaluate the lipid profile levels of patients who had experienced an acute stroke during the first 24-hour and to compare these levels in different patients suffering from the stroke, eithe...

OBJECTIVE SNPs identified from genome-wide association studies associate with lipid risk markers of cardiovascular disease. This study investigated whether these SNPs altered the plasma lipid response to diet in the 'RISCK' study cohort. METHODS Participants (n=490) from a dietary intervention to lower saturated fat by replacement with carbohydrate or monounsaturated fat, were genotyped for 3...