Timothy M. Crowder, PhD, is chief technology officer at Oriel Therapeutics, Inc., PO Box 14087, Research Triangle Park, NC 27709, tel. 919.313.1290 ext. 11, fax 919.313.1295, [email protected]. ctive dry-powder inhalers (DPIs) for pulmonary drug delivery have been under development for at least 10 years, but to date no such device has been approved by FDA. Like propellant-driven me...

The nasal absorption of macromolecules from powder formulations and the effect of sodium carboxymethyl cellulose (CMC-Na) as a pharmaceutical excipient on their absorption were studied. Model macromolecules were fluorescein isothiocyanate-labeled dextran (average molecular weight of 4.4kDa, FD4) and insulin. The plasma concentration of FD4 after application of the powder containing 50% starch (...

The purpose of the present study was to evaluate the effects of red pepper seeds powder on lipid metabolism in rats fed high fatᆞhigh cholesterol diet. Rats were divided into five experimental groups: normal diet group, high fatᆞhigh cholesterol diet group, high fatᆞhigh cholesterol diet with 5% red pepper seeds powder supplemented group (SA group), high fatᆞhigh cholesterol diet with 10% red p...

mold powders used in the continuous casting of steel contain the harmful caf2 as a main substance developing toxic gases such as sif4 and hf at elevated temperatures. in this study, three samples of i1, i2 and i3, which contained gypsum free portland cement clinker with different percentages of fe2o3 (5.68, 6.83, 8.02 ) and f- (2.09, 1.06, 0), were prepared and their main characteristics were c...

Title IV of the 1990 Clean Air Act Amendments introduced a cap-and-trade system for sulfur dioxide emissions from electric power plants in the United States. This paper analyzes the effects of that regulatory change on the prices charged by the two railroads that hauled low-sulfur coal east from Wyoming. We estimate the effect of the tradeable permits regime by comparing prices at affected plan...

BACKGROUND Due to its diverse geographical and habitat conditions, northern Pakistan harbors a wealth of medicinal plants. The plants and their traditional use are part of the natural and cultural heritage of the region. This study was carried out to document which medicinal plant species and which plant parts are used in the region of Swat, which syndrome categories are particularly concerned,...

Thermochemcial characteristics of powder fabricated using oxidation treatment of spent PWR fuel and SIMFUEL were evaluated for recycling of spent fuel such as DUPIC process. Especially, the influence of spent fuel burn-ups on the powder fabrication characteristics was experimentally evaluated, ranging from 27,300 to 65,000 MWd/tU. Densities of powder manufactured from an oxidation, OREOX and th...