Plants are natural sources of bioactive compounds, and the intensive use wild plants to obtain them, in particular secondary metabolites, depletes biocenoses. Instead, modern biotechnological methods, especially cell tissue culture vitro, make it possible get environmentally friendly, highly productive plant raw materials that able synthesize accumulate specialized substances, which valuable fo...

The mechanism whereby organisms interact and differentiate between others has been at the forefront of scientific inquiry, particularly in humans and certain animals. It is widely accepted that plants also interact, but the degree of this interaction has been constricted to competition for space, nutrients, water and light. Here, we analyzed the root secreted metabolites and proteins involved i...

Endophytes are microbes that inhabit host plants without causing disease and are reported to be reservoirs of metabolites that combat microbes and other pathogens. Here we review diverse classes of secondary metabolites, focusing on anti-microbial compounds, synthesized by fungal endophytes including terpenoids, alkaloids, phenylpropanoids, aliphatic compounds, polyketides, and peptides from th...

Trichoderma fungi release 6-pentyl-2H-pyran-2-one (1) and harzianic acid (2) secondary metabolites to improve plant growth and health protection. We isolated metabolites 1 and 2 from Trichoderma strains, whose different concentrations were used to treat seeds of Solanum lycopersicum. The metabolic profile in the resulting 15 day old tomato leaves was studied by high-resolution magic-angle-spinn...

Production of a bioherbicide for biological control of weeds requires a series of steps, from selection of a suitable microbial strain to final formulation. Thus, this study aimed to select fungi for production of secondary metabolites with herbicidal activity using biological resources of the Brazilian Pampa biome. Phytopathogenic fungi were isolated from infected tissues of weeds in the Pampa...

The benzylisoquinoline alkaloids (BIAs) are a diverse class of plant secondary metabolites that exhibit a broad range of pharmacological activities and are synthesized through biosynthetic pathways that exhibit complex enzyme activities and regulatory strategies. We have engineered yeast to produce the major branch point intermediate reticuline and downstream BIA metabolites from a commercially...

Synergism and antagonism impact of different plant metabolites present in crude fruit extract of Tribulus terrestris 'the herbal Viagra' have been studied. Variability in plant composition, biomass and metabolites concentration in different modules was significantly contributed by spatial factor. However the edhaphic parameters also changes with both spatial and temporal factors significantly. ...