A novel G11-protein-coupled receptor specific for synthetic GH-releasing peptides (GHRPs) has recently been cloned and sequenced. Two forms exist, types 1a and 1b, the latter of which is biologically inactive. Using RT-PCR, we looked for the presence in tumorous pituitary cells of messenger ribonucleic acid (mRNA) for this novel GH secretagogue receptor (GHS-R). Both subtypes of GHS-R mRNA were...

OBJECTIVE Endogenous Cushing syndrome in children is a rare disorder that is most frequently caused by pituitary or adrenocortical tumors. Diagnostic criteria have generally been derived from studies of adult patients despite significant differences in both the physiology of the hypothalamic-pituitary-adrenal axis and the epidemiology of Cushing syndrome in childhood. The purpose of this study ...

Magnetic resonance imaging (MRI) combined with artificial intelligence (AI) algorithms to detect brain tumors is one of the important medical applications. In this study, a Convolutional neural network (CNN) model proposed meningioma and pituitary, which was tested dataset consisting two categories 1,800 MRI images from several persons. The CNN trained via Python library, namely TensorFlow, an ...

AIM Pituitary tumors are generally benign, but may be associated with some morbidities. The aim of this study was to identify the risk factors for pituitary tumors. MATERIAL AND METHODS A population-based case-control study on the potential risk factors of pituitary tumors was conducted in China. The personal interview technique was used to gather information on medical and reproductive histo...

Pituitary adenomas cause significant morbidity caused by compression of regional structures or the inappropriate expression of pituitary hormones. However, little is known about the molecular changes that contribute to the development of these tumors. To investigate these changes, we recently used cDNA microarray analysis to identify several genes with altered expression patterns in pituitary a...

Pituitary tumors account for more than 10% of all intracranial tumors. They often present with symptoms of hormonal hypersecretion, although they may also cause hypopituitarism. Transsphenoidal pituitary surgery has become a commonly performed neurosurgical procedure, which has certain challenges for the anesthesiologist due to many distinct comorbidities associated with various adenomas. This ...