OBJECTIVE Previous research has demonstrated that prefrontal activity is related to control over stress responses. However, the causal mechanisms are not well understood. In this study we investigated the possible influence of brain stimulation on the physiological stress response system. Because an increased stress response is known to precipitate psychiatric disorders, further inquiry can hav...

Changes in calcium and redox homeostasis influence multiple cellular processes. Dysregulation of these signaling modalities is associated with pathology in cardiovascular, neuronal, endocrine, and other physiological systems. Calcium and oxidant signaling mechanisms are frequently inferred to be functionally related. To address and clarify this clinically relevant issue in the vasculature we te...

A significant proportion of severe psychological problems in recent large-scale peacekeeping operations underscores the importance of effective methods for strengthening the stress resilience. Virtual reality (VR) adaptive stimulation, based on the estimation of the participant's emotional state from physiological signals, may enhance the mental readiness training (MRT). Understanding neurobiol...

1. Ornithine decarboxylase activity is stimulated in high-density HeLa-cell cultures by dilution of or replacement of spent culture medium with fresh medium containing 10% (v/v) horse serum. 2. After stimulation, ornithine decarboxylase activity reaches a peak at 4-6h, then rapidly declines to the low enzyme activity characteristic of quiescent cultures, where it remains during the remainder of...

Signals in functional magnetic resonance imaging (fMRI) are influenced by physiological fluctuations in addition to local brain activity. We have proposed a dynamic system model-based technique for separation of signal changes related to brain activation inputs from those related to physiological fluctuations. We applied this technique to a visual fMRI experiment to determine the validity and f...

In 1890, William James hypothesized that emotions are our perception of physiological changes. Many different theories of emotion have emerged since then, but it has been demonstrated that a specifically induced physiological state can influence an individual's emotional responses to stimuli. In the present study, auditory and/or vibrotactile heartbeat stimuli were presented to participants (N ...

BACKGROUND/AIMS Regulatory volume decrease (RVD) in response to acute cell swelling is well described and KCNK5 (also known as TASK-2 or K2P5.1) has been shown to be the volume sensitive K(+) channel in Ehrlich cells. Very little is, on the other hand, known about the effects of long-term hypotonicity on expression and function of KCNK5, thus we have investigated the effect of long-term hypoton...

Lack of knowledge latex harvesting techniques from Hevea brasiliensis clones results in a high rate unproductive trees and drop rubber production. In order to improve these determine the stimulation regime allowing express their production potential, study was undertaken for 6 years south-eastern part Ivory Coast. It focused on with active metabolism (IRCA 111 IRCA 130) planted at density 510 /...

For >20 years, noninvasive transcranial stimulation techniques like repetitive transcranial magnetic stimulation (rTMS) and direct current stimulation (tDCS) have been used to induce neuroplastic-like effects in the human cortex, leading to the activity-dependent modification of synaptic transmission. Here, we introduce a novel method of electrical stimulation: transcranial random noise stimula...

The physiology and pharmacology of CA1 is changed in epilepsy. There is evidence that the thalamic input to CA1 has a somewhat different physiological effect compared with the CA3 input. In this study we sought to determine whether this difference in physiology persists in epilepsy, and whether there are changes in the pharmacologic profile of these responses. Under urethane two stimulating ele...