The article provides an overview of scientific information on modern approaches to reproductive health protection, innovative methods for early detection disorders and timely correction reduced capabilities the body, including infertility. main physiological factors are genetic predisposition, mitochondrial dysfunctions, genomic instability, oxidative stress, etc. In particular, mitochondria ma...

Mood and anxiety disorders are heterogeneous psychiatric diagnoses affecting millions. While the disease etiology is complex, various risk factors have been identified, such as stress. Stress a neuroendocrine physiologic response to stressor that promotes organism survival through adaptive processes behavior. The central stress response, which drives behavioral physiological change, primarily m...

Mesenchymal stem/stromal cells (MSCs) and fibroblasts are present in normal tissues to support tissue homeostasis. Both share common pathways have a number of features, such as spindle-shaped morphology, connective localization, multipotency. In inflammation, nonspecific response injury, MSC the main players. Two mechanisms their mode action been defined: immunomodulation regeneration. Followin...

Ageing is a complex process that greatly influenced by environmental and genetic factors. at the cellular molecular level characterized accumulation of post-translationally modified proteins are derogative to cells, termed Degenerative protein modification (DPM). A particular class DPM, occurring under impact urea, brain ureido degenerative post-translational modifications (uDPM) has also been ...

The transition from childhood to adolescence is a period of life characterized by hormonal and physiological changes. In this phase, there are also several social interactions that change according the environment, imposing responsibilities desire for new cycles. These demands make people vulnerable insecure certain feelings, generating mood disorders can progress major depression disorder. Obj...

RTP801/REDD1 is a stress-regulated protein whose upregulation necessary and sufficient to trigger neuronal death in vitro vivo models of Parkinson's Huntington's diseases up regulated compromised neurons human postmortem brains both neurodegenerative disorders. Indeed, disease mouse models, RTP801 knockdown alleviates motor-learning deficits. We investigated the physiological role plasticity we...

The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying setpoints of bodily needs and competing motivations. Allost...

Vagus nerve stimulation (VNS) is a technology that provides electrical to the cervical vagus and can be applied in treatment of wide variety neuropsychiatric systemic diseases. VNS exerts its effect by stimulating vagal afferent efferent fibers, which project upward brainstem nuclei relayed circuits downward internal organs influence autonomic, neuroendocrine, neuroimmunology systems. The neuro...

Phoniatry is a branch of otorhinolaryngology and deals with issues related to the diagnosis, treatment prevention voice disorders. Violations function, especially in persons voice-speaking professions, worsen quality life, affect interpersonal relationships, create difficulties communication, some cases lead professional unfitness. It known that about 6% population suffers from disorders, laryn...