Previously, flaviolin was isolated from the blackish culture solution of Phoma wasabiae [1]. In continuation of the study on the metabolites of this mold, we have now isolated 2-hydroxy-6-methoxy-3,5-dimethyl-l,4-benzoquinone. This benzoquinone was already synthesized [2], but has not been found as a natural product. In this paper we wish to report on the isolation of the above quinone from the...

endophytes are considered as an important source of bioactive natural products because thesemicroorganisms are able to occupy unique biological niches and grow in non-ordinaryenvironments. therefore, endophytic fungi of medicinal plants can be developed for medicinalapplications. on the other hand, medicinal properties of plant can be ascribed to its endophyticfungi. thymus sp. is widely used a...

In this research,for taxonomic studies and identification of the fungi associated with the powdery mildew(Oidium euonymi- japonici) of Buxus trees (Euonymus japonica), the infected leaves were collected during autumn and winter 2012-2013 in Gorgan (Golestan province -Iran). The samples after washing and surface sterilizing, were cultured on PDA medium(with boxwood extract).Then based on availab...

Two new polyketides, arthropsadiol C (1) and massarilactone H (2), together with six known derivatives (3-8) were isolated from the culture broth of the marine-derived fungus Phoma herbarum. Their structures were elucidated on the basis of spectroscopic methods, including 2D NMR techniques. Compounds 2, 4, 5, and 8 showed moderate neuraminidase inhibitory activity with IC(50) values ranging fro...

Incorporation of [l3C,2H3-CHs]-L-methionine into cytochala-: sin A (I), cytochalasin B (II), proxiphomin (III) and protophomin (IV) by Phoma exiqua var. exiqua demonstrated that the two C-methylations occur with retention of all three H-atoms of the methyl group. Conclusions are drawn concerning the stage of the methylation reaction during the biogenetic pathway. On the basis of the results amo...

Endophytic fungi were isolated from various tissues (root, stem, petiole, leaf, and fl ower stalk) of 3- and 4-year-old ginseng plants (Panax ginseng Meyer) cultivated in Korea. The isolated endophytic fungi were identified based on the sequence analysis of the internal transcribed spacer (ITS), 1-5.8-ITS 2. A morphological characterization was also conducted using microscopic observations. Acc...