In the bloodstream of its mammalian host, the African trypanosome Trypanosoma brucei undergoes a life cycle stage differentiation from a long, slender form to a short, stumpy form. This involves three known major events: exit from a proliferative cell cycle, morphological change and mitochondrial biogenesis. Previously, models have been proposed accounting for these events (Matthews & Gull 1994...

Fruit shape is one of the most important quality factors in many domesticated plants. In this study, we used bulked segregate analysis (BSA) to identify two sequence-related amplified polymorphism (SRAP) markers linked to fruit shape in cucumber (Cucumis sativus L.). A segregating F2 population of 130 plants from a cross (B-2-2×Y-3) of B-2-2 with long fruit shape trait and Y-3 with round fruit ...

Th e paper presents numerical comparison of two methods of estimation of nonallelic interaction of QTL eff ects. In the fi rst method we assume that we observe only the plant phenotype, while in the second method we have additional information from the molecular markers observations. In this paper we analysed phenotypic data on 120 barley doubled haploid lines, derived from cross Clipper × Saha...

Association analysis is a useful method for evaluation of significant association between molecular marker and phenotype of trait. This study was performed to evaluate association between traits related with powdery mildew resistance and molecular markers. This investigation was performed using 77 barley genotypes and AFLP markers. In phenotypic evaluation, reaction of seedlings to powdery mild...

the cytoplasmic male sterile (cms) lines that are used in production of hybrid seeds in three-line system often get contaminated with their maintainer lines. using such impure cms lines in rice hybrid seed production lead to un-uniformity and yield loss in hybrid rice. laborious and time consuming phenotypic evaluations are used for elimination of off-type plants in cms multiplication farms. th...

ABSTRACT We used molecular markers to identify quantitative trait loci (QTL) that confer resistance in the field to Xanthomonas campestris pv. vesicatoria race T1, a causal agent of bacterial spot of tomato. An F(2) population derived from a cross between Hawaii 7998 (H 7998) and an elite breeding line, Ohio 88119, was used for the initial identification of an association between molecular mark...

Cichlid species of the genus Oreochromis vary in their genetic sex-determination systems. In this study, we used microsatellite DNA markers to characterize the sex-determination system in Oreochromis tanganicae. Markers on linkage group 3 were associated with phenotypic sex, with an inheritance pattern typical of a female heterogametic species (WZ-ZZ). Further, locus duplication was observed fo...

Introduction More than 1000 morphological markers have been identified in barley (Franckowiak and Lundqvist 2002). These phenotypic traits were observed as spontaneous or artificially generated mutants in a wide range of cultivars over decades of research. Traits identified with alternate alleles include plant height, spike morphology, and seed size, among others. Approximately 275 of these mar...

BACKGROUND Fibroblastic foci are characteristic features in lung parenchyma of patients with idiopathic pulmonary fibrosis (IPF). They comprise aggregates of mesenchymal cells which underlie sites of unresolved epithelial injury and are associated with progression of fibrosis. However, the cellular origins of these mesenchymal phenotypes remain unclear. We examined whether the potent fibrogenic...

Mineral nutrient malnutrition, particularly deficiency in zinc and iron, afflicts over 3 billion people worldwide. Biofortification of food crops is the best approach for conciliating the micronutrient deficiencies. Understanding the genetic basis of their accumulation is the preconditions for enhancing of these micronutrients. In our study, a mapping population of a set of 118 recombinant inbr...