نتایج جستجو برای: phenformin

تعداد نتایج: 275  

Objective(s): Breast cancer remains a global challenge, and further chemopreventive therapies are still immediately required. Emerging evidence has revealed the potent anti-cancer effects of biguanides, Metformin (MET) and phenformin (PHE). Thus, to explore an efficient chemopreventive strategy for breast cancer, the antiproliferative effects of the combination of MET and PHE against breast can...

Journal: :Frontiers in bioscience 2023

Background: Activation of the unfolded protein response (UPR) is closely related to pathogenesis many metabolic disorders. Accumulating evidence also shows that UPR and signaling pathways are interdependent. The AMP-activated kinase (AMPK) signal pathway controls energy balance eukaryotes. aim this study was therefore investigate possible interaction between AMPK in muscle cells exposed saturat...

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