Homologous recombination (HR) and non-homologous end joining (NHEJ) represent distinct pathways for repairing DNA double-strand breaks (DSBs). Previous work implicated Artemis and ATM in an NHEJ-dependent process, which repairs a defined subset of radiation-induced DSBs in G1-phase. Here, we show that in G2, as in G1, NHEJ represents the major DSB-repair pathway whereas HR is only essential for...

0950-5849/$ see front matter 2009 Elsevier B.V. A doi:10.1016/j.infsof.2009.08.002 * Corresponding author. E-mail addresses: [email protected] (A. Gupta [email protected] (R. Conradi), haro@statoilhydro statoilhydro.com (E. Landre). Software reuse is expected to improve software productivity and quality. Although many empirical studies have investigated the benefits and challenges of softw...

This paper introduces and studies a declarative framework for updating views over indefinite databases. An indefinite database is a database with null values that are represented, following the standard database approach, by a single null constant. The paper formalizes views over such databases as indefinite deductive databases, and defines for them several classes of database repairs that real...

A relational database is inconsistent if it does not satisfy a given set of integrity constraints. Nevertheless, it is likely that most of the data in it is consistent with the constraints. In this paper we apply logic programming based on answer sets to the problem of retrieving consistent information from a possibly inconsistent database. Since consistent information persists from the origina...

BACKGROUND Complete radial tears of the medial meniscus have been reported to be functionally similar to a total meniscectomy. At present, there is no consensus on an ideal technique for repair of radial midbody tears of the medial meniscus. Prior attempts at repair with double horizontal mattress suture techniques have led to a reportedly high rate of incomplete healing or healing in a nonanat...

BACKGROUND Injuries to the superior glenoid labrum represent a significant cause of shoulder pain among active patients. The physical requirements of military service may contribute to an increased risk of injury. Limited data are available regarding the success of superior labral anterior posterior (SLAP) repairs in an active military population. PURPOSE To quantify the rate of clinical fail...

Surgeons must rely on cost and charge data to inform a patient outcome–optimized value-based approach arthroscopic rotator cuff repairs. Using biologic regenerative procedures augment repairs only when necessary optimizing anchor number are 2 obvious ways surgeons can help control of these procedures. Addition biologics, such as patches tissue augmentation, nearly doubled the charges for proced...

In this paper, we study the strong stability in the M/G/1 queueing system with breakdowns and repairs after perturbation of the breakdown’s parameter. Using the approximation conditions in the classical M/G/1 system, we obtain stability inequalities with exact computation of the constants. Thus, we can approximate the characteristics of the M/G/1 queueing system with breakdowns and repairs by t...

This paper describes a noisy channel model of speech repairs, which can identify and correct repairs in speech transcripts. A syntactic parser is used as the source model, and a novel type of TAG-based transducer is the channel model. The use of TAG is motivated by the intuition that the reparandum is a “rough copy” of the repair. The model is trained and tested on the Switchboard disfluency-an...

This paper describes a time-series model for parsing transcribed speech containing disfluencies. This model differs from previous parsers in its explicit modeling of a buffer of recent words, which allows it to recognize repairs more easily due to the frequent overlap in words between errors and their repairs. The parser implementing this model is evaluated on the standard Switchboard transcrib...