BACKGROUND Atropine decreases the frequency of transient lower oesophageal sphincter relaxation (TLOSR) through an unknown mechanism. Gastric distension and pharyngeal receptor excitation are two possible sources for the afferent stimulus responsible for TLOSR. AIMS To determine whether atropine affects gastric distension induced TLOSR and pharyngeal receptor mediated lower oesophageal sphinc...

It has been hypothesized that the pressure in tissues surrounding the upper airway is one of the determinants of the size and shape of the upper airway. To our knowledge, this pressure has not been measured. The purpose of this study was to test whether the pressure in a tissue lateral to the upper airway, the lateral pharyngeal fat pad pressure (Pfp), differs from atmospheric and pharyngeal pr...

The phenotypes of skeletal malformations induced in pharyngeal arches and pectoral fins of Ž . X Japanese flounder larvae by retinoic acid RA , disulfiram, 2,2 -dipyridyl and azetidine-2-carboxylic acid were characterized, RA controls gene expression essential for pharyngeal and pectoral fin development; disulfiram is an inhibitor of RA synthase, 2,2-dipyridyl and azetidine-2-carboxylic acid ar...

An acute wheezing episode is the most common feature of severe lower respiratory tract infection during infancy. Respiratory syncytial virus (RSV) is the major causative agent. In order to study inflammation during acute wheezing episodes in infants, we wanted to assess the feasibility and contribution of induction of pharyngeal secretions. We therefore compared inflammatory markers in the phar...

OBJECTIVES The study was aimed to evaluate the pharyngeal airway linear measurements of untreated skeletal class II subjects with normal facial vertical pattern in prognathic maxilla with orthognathic mandible and orthognathic maxilla with retrognathic mandible. MATERIALS AND METHOD the sample comprised of lateral Cephalograms of two groups (30 each) of class II malocclusion variants. Group 1...

This prospective cohort study evaluated the use of videofluoroscopy in assessing changes in both antero-posterior (A-P) and transverse pharyngeal airway dimensions in patients with obstructive sleep apnoea (OSA). Forty patients [32 males and 8 females; mean age of 49.3 (SD = 10.79) years] with confirmed OSA, referred for mandibular advancement appliance (MAA) therapy were recruited. Patients re...

The thymus is an organ for T lymphocyte maturation and is indispensable for the establishment of a highly developed immune system in vertebrates. In order to genetically dissect thymus organogenesis, we carried out a large-scale mutagenesis screening for Medaka mutations affecting recombination activating gene 1 (rag1) expression in the developing thymus. We identified 24 mutations, defining at...

OBJECTIVE The study was performed to compare the 3D pharyngeal airway dimensions in adult skeletal Class II patients with different vertical growth patterns (low, normal, and high angle) and to investigate whether the upper airway dimensions of untreated skeletal Class II adults were affected by vertical skeletal variables. METHODS Cone-beam computed tomography (CBCT) records of 64 untreated ...

INTRODUCTION Nausea and vomiting after ear, nose and throat (ENT) surgery is one of the most common and notable problems facing anesthesiologists in this area. This study was conducted to determine the effect of a pharyngeal pack on the severity of nausea, vomiting, and sore throat among patients after ear, pharynx, and throat surgeries. MATERIALS AND METHODS This randomized clinical study wa...

INTRODUCTION The purposes of this study were to assess the effects of maxillary protraction therapy on the pharyngeal airways in patients with repaired unilateral cleft lip and palate (UCLP) 3 dimensionally. METHODS Eighteen patients with repaired UCLP and anterior crossbite (ages, 10.4 ± 1.3 years) were enrolled in the study group. Hyrax appliances and reverse headgears were used. Cone-beam ...