Different hexoprenaline (Hx(2)SO(4)) conventional and coated wire electrodes were constructed and evaluated. Membranes were based on hexoprenalinium phosphotungstate (Hx-PTA) and hexporenalinium phosphomolybdate (Hx-PMA). The electrodes were fully characterized in terms of their composition, response time, life span, pH, and temperature and then were applied to the potentiometric determination ...

Address correspondence to S. Carda Broch. endroflumethiazide (BMFT [RS]-3-phenylmethyl-3,4-dihydro-6-trif luoromethyl-2H1,2,4-benzothiadiazine-7-sulfonamide-1,1dioxide) is a potent diuretic drug extensively used for the treatment of hypertension and oedema that belongs to the thiazide family (1). BMFT is well absorbed from the gastrointestinal tract after oral administration and the absorption ...

INTRODUCTION Pipemidic acid (PA) is a synthetic quinolone that belongs to the first generation of this kind of compounds, which is used as antibacterial agent. The antibacterial property of the quinolones is associated with their potential to inhibit the bacterial topoisomerase II (1). PA is widely used for the treatment of urinary tract infections, showing high activity against gram-positive a...

There is an increasing interest in new strategies to determine as well as assessment of drugs in medical and pharmaceutical sciences. Herein we describe a simple, rapid, sensitive, and selective spectrophotometric method for determination of labetalol (LBT) hydrochloride based on the oxidation of the drug with ferric ammonium sulphate that yields a green colored product. The increase in absorba...

Pregabalin (PGB), is an antiepileptic and analgesic drug, which is structural analogue of γ-amino-butyric acid. This drug has been approved by Food and Drug Administration for the treatment of central nervous system disorders including epilepsy, fibromyalgia and also for the treatment of neuropathic pain. It was designed as a potent successor to gabapentin. PGB is minimally metabolized and prim...