In this work the electrooxidation half-wave potentials of some Benzoxazines were predicted from their structural molecular descriptors by using quantitative structure-property relationship (QSAR) approaches. The dataset consist the half-wave potential of 40 benzoxazine derivatives which were obtained by DC-polarography. Descriptors which were selected by stepwise multiple selection procedure ar...

Net analyte signal statistical quality control (NAS-SQC) is a new methodology to perform multivariate product quality monitoring based on the net analyte signal approach. The main advantage of NAS-SQC is that the systematic variation in the product due to the analyte (or property) of interest is separated from the remaining systematic variation due to all other compounds in the matrix. This enh...

background and objectives: pharmaceutical expenditures are responsible for a major part of health systems’ cost. according to the who’s statistics, iran is the first among the 20 countries in the world in terms of drug consumption. the first step in controlling consumption of a particular good is to identify factor inducing the relevant demands. hence, this study aimed to identify the pattern a...

The aim of this study was to evaluate the compaction property of several pharmaceutical materials by measuring the die wall pressure. The profile of die wall force during tabletting process was measured with the compaction process analyzer (TabAll). Several compaction parameters such as maximum die wall pressure (MDP), residual die wall pressure (RDP) and pressure transmission ratio (PTR) from ...

South Africa is a middle-income country with the world's largest HIV patient cohort and a growing burden of communicable and non-communicable diseases - a prime location for pharmaceutical companies looking to expand their markets. Yet, 20 years after the country's first democratic elections, poor health indicators and an over-burdened public health system belie persistently stark levels of soc...

Plants gums are complex mixtures of different polysaccharides with a variety of biological activities and pharmaceutical applications. Few studies have focused on physicochemical and biological properties of gums obtained from different plants. This study was designed to determine potential pharmaceutical and pharmacological values of the gum exudates and its isolated biopolymers obtained from ...

The unexpected enhancement of alkalinee phosphatase (ALP) activity in the serum of a group of STZ-diabetic rats recieving the Teucrium polium extract (with hypoglycaemic property) may be attributed to its probable side effects. In order to get a more precise knowledge about this subject, we evaluated the effect of T. polium extract on the plasma membrane ALP activity of K562 cell line. Our data...

Over the past two decades, the role of intellectual property rights in all areas of science and technology has exploded globally– primarily due to the rules prescribed by the World Trade Organization’s TRIPS and by bilateral/regional trade agreements. The TRIPS agreement obligates all WTO member countries to adopt and enforce minimum standards of intellectual property rights. The TRIPS agreemen...

Objective(s): Today, there is an urgent need for improved sensor materials for drug sensing and effective monitoring and interventions in this area are highly required to struggle drug abuse. The present study aimed to synthesize a thioguanine-responsive sensor based on a nanocomposite consisting of AuNP-grafted light- and temperature-responsive poly butylmethacrylate-co-acrylamide-co-methacryl...

When using shear testing to determine wall friction of pharmaceutical particulate systems, it is crucial to measure at the correct wall normal stress. By comparing data obtained at a wall normal stress of 1000 to 200 Pa, the effect of the applied stress on the accuracy and precision of the method was assessed. INTRODUCTION When powder flows under gravity from a hopper, it follows one of two pat...