to be sure, all the industries try to be involved in globalization with a constant trend to find out ways to increase productivity across different functions within an organization to maintain competitive advantage world. pharmaceutical industries are not exceptional and further are based on fragmentation. so these kind of companies need to cope with several barriers such as silo mentality that...

one hundred and fifteen prescriptions which were purposely written in toxic and potentially fatal dose of different medicine (mainly digitoxin) were sent to pharmacies throughout iran. all pharmacies filled up the prescription and only one pharmacist made notice of dangerous dose. the pharmacist in the drugstores in iran is forcefully employed by the owner of the pharmacy which is required by l...

Microencapsulation is highly attractive for oral drug delivery. Microparticles are a common form of drug carrier for this purpose. There is still a high demand on efficient methods to fabricate microparticles with uniform sizes and well-controlled particle properties. In this paper, uniform hydroxypropyl methylcellulose phthalate (HPMCP)-based pharmaceutical microparticles loaded with either hy...

Editorials 67 Meeting the high and increasing price of medicines for rare disorders is an ongoing dilemma for patients, insurers and governments worldwide. In New Zealand, the difficulty has been highlighted by lobbyists campaigning for funding eculizumab for paroxysmal nocturnal haemoglobinuria and for enzyme replacement therapies including alglucosidase alfa for glycogen storage disease type ...

The well-recognized limitations of traditional randomized, controlled trials (RCTs), including their cost, the nature of the patients and providers included in them, and even the types of interventions that they can evaluate, have led to the search for alternative methods and settings for conducting these types of studies. Pragmatic trials,1 also referred to as “practical” or “effectiveness” tr...

conclusions carriage of pvl-positive s. aureus is common in this region, even in the low frequency of mrsa colonization. the detection of acme-arca gene in s. aureus isolates is a public-health concern and demands continued surveillance and close monitoring. results among the 813 subjects screened, 83 (10.2%) were persistent carriers, 86 (10.6%) were transient carriers and 644 (79.2%) cases wer...

UNLABELLED Nonadherence to medication treatment regimens is a major preventable risk behavior in both acute and chronic diseases. Community pharmacists are facilitators in community care for promoting medication adherence and they should implement interdisciplinary medication adherence programs. To do so, pharmacists should be educated in medication adherence, and new pharmaceutical care polici...

The objective of this study is to develop suitable formulations to improve the dissolution rate of poorly water soluble drugs. We selected lipid-based formulation as a drug carrier and modified the surface using positively charged chitosan derivative (HTCC) to increase its water solubility and bioavailability. Chitosan and HTCC-coated lipid particles had higher zeta-potential values than uncoat...

BACKGROUND The therapeutic use of cannabis and cannabis-based medicines raises safety concerns for patients, clinicians, policy-makers, insurers, researchers and regulators. Although the efficacy of cannabinoids is being increasingly demonstrated in randomized controlled trials, most safety information comes from studies of recreational use. METHODS We performed a systematic review of safety ...

Polysaccharides are inspiring and valuable molecules to the development of novel drug delivery systems owing their natural availability, non-toxicity, biocompatibility, good biological performance, chemical similarity physiological environment, besides noticeable use for tailored-materials assembly. Biodegradable hydrogels based on polysaccharides have been widely studied as potential pharmaceu...