Parallel Fragmentation Monitoring (PFM), which is an analogue of selected reaction monitoring (SRM), is a recently developed method for quantification of small molecules by MALDI-TOF/TOF mass spectrometry (MS). It is well known that isobaric interference substances can be occasionally present in complex biological samples, and affect the accuracy of measurement by SRM. Unfortunately, by design ...

The forces acting on an optically trapped particle are usually assumed to be conservative. However, the presence of a non-conservative component has recently been demonstrated. Here we propose a technique that permits one to quantify the contribution of such a non-conservative component. This is an extension of a standard calibration technique for optical tweezers and, therefore, can easily bec...

Detailed analysis of data from studies of recombinant antihemophilic factor produced using a plasma/albumin-free method (rAHF-PFM) in previously treated patients showed a substantial level of interpatient variation in pharmacokinetics (PKs), factor VIII dosing, and annualized bleed rate (ABR), suggesting that individual patient characteristics contributed to outcome. For example, plasma half-li...

Pelvic floor muscles (PFM) play an important role in maintaining urinary continence with increasing age. Therefore, their contractile properties need to be evaluated. The aim of the study was to examine the reliability and correlation of simple techniques to measure PFM strength in elderly women with urinary incontinence. An interview was used to evaluate the ability to stop the urinary stream ...

We report a prospective trial of 55 previously untreated patients (PUPs) and minimally treated patients (MTPs) with severe/moderately severe haemophilia A (baseline factor VIII [FVIII] ≤2%) treated with a single FVIII replacement product. It was the objective of this study to evaluate the immunogenicity, efficacy, and safety of rAHF-PFM (Advate®). On-demand or prophylactic treatment regimens we...

STATEMENT OF PROBLEM Recent clinical results for Zirconia all-ceramic restorations have revealed that the fracture rate 6-15% of the Zirconia framework is so low and the core of Zirconia has high stability. However, chipping-off fractures of porcelain are the most common reason for failures of Zirconia in the fixed partial dentures. OBJECTIVES The purpose of this study was to compare the shea...

This paper presents for a web-based learning system two models we have named the patterned frame model (PFM), and the synchronized presentation model (SPM).

pomegranate fruit moth (pfm), apomyelois ceratoniae zeller is a major pest of pomegranate in iran. in this study, the effect of four diets including pistachio, pomegranate, semi-artificial and artificial diets were studied on biological parameters of pfm in a growth chamber under controlled conditions at 30 ± 2 °c, 65 ± 5% rh and 16:8 (l: d) h. the results demonstrated that the longest incubati...

Lactobacillus rhamnosus GG, Lactobacillus paracasei TMC0409, Streptococcus thermophilus TMC1543 and whey proteins were used to prepare fermented milk. For the experiment aP2- agouti transgenic mice were pre-treated with a high-sucrose/high-fat diet for 6 weeks to induce obesity. The obese mice were fed a diet containing 1·2% Ca and either non-fat dried milk (NFDM) or probiotic-fermented milk (P...

Résumé. Cet article traite de la représentation formelle de la morphologie des noms et des verbes de l’ikota, langue bantoue du Gabon. J’utilise la notion de classes de position (CP) de la PMF (Paradigm Function Morphology), théorie morphologique qui s’intéresse à la flexion. Les noms et les verbes seront représentés en fonction de leurs CP. Ce procédé sera réutilisé dans le langage XMG (eXtens...