The present study was designed to determine whether hyperoxia would lower the hypocapnic apneic threshold (AT) during non-rapid eye movement (NREM) sleep. Nasal noninvasive mechanical ventilation was used to induce hypocapnia and subsequent central apnea in healthy subjects during stable NREM sleep. Mechanical ventilation trials were conducted under normoxic (room air) and hyperoxic conditions ...

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation exposure. To minimize this potential risk in PET imaging, efforts have been made to reduce the amount of radiotracer usage. However, lowing dose results in low ...

INTRODUCTION Myocardial perfusion scintigraphy (MPS) is an established non-invasive technique for the diagnosis and management of patients with suspected or known coronary artery disease. Because of the wealth of prognostic data, MPS single photon emission computed tomography (SPECT) is the most commonly used functional test to detect inducible ischaemia. However, the increasing availability of...

BACKGROUND/AIM To investigate the effect of positron emission tomography-computed tomography (PET/CT)-based contouring on dosimetric parameters in rectal cancer patients undergoing preoperative intensity-modulated radiation therapy (IMRT). MATERIALS AND METHODS Preoperative radiation therapy plans with conformal radiotherapy (CRT) or IMRT were created and examined according to the CT- and PET...

A complete and permanent hydrophilic modification of poly (ethyleneterephthalate) (PET) films is achieved by argon-plasma irradiation, subsequently grafting acrylic acid (AA) in vapor phase onto their surface. Both Ar plasma irradiation alone and post grafting AA rendered a complete hydrophilicity to PET surfaces. However, the hydrophilicity of the PET surface, only treated with the Ar plasma, ...

UNLABELLED A quantitative PET imaging method was used to assess the in vivo kinetics of hepatobiliary and renal excretion of the breast cancer resistance protein (Bcrp) substrate (11)C-SC-62807 in mice. METHODS Serial abdominal PET scans were collected in wild-type and Bcrp knockout (Bcrp(-/-)) mice after intravenous injection of (11)C-SC-62807. Venous blood samples and PET images were obtain...

Brunotte F, Haas H, Collin B, Oudot A, Bricq S, Lalande A, Tizon X, Vrigneaud JM, Walker PM. Integrated PET/ MRI in preclinical studies. State of the art. The exquisite tissue contrast of magnetic resonance imaging (MRI), the absence of ionising radiation and the opportunity to obtain new molecular and functional data have strengthened the enthusiasm for coupling MRI rather than computed tomogr...

BACKGROUND Exposure to pets in childhood has been associated with a reduced risk of wheezing and atopy. OBJECTIVE Our objective was to determine whether the effects of pet exposure on immune development and atopy in early childhood can be explained by alterations in exposure to innate immune stimuli in settled dust. METHODS Two hundred and seventy-five children at increased risk of developi...

objective(s): the aim of this study was to analyze detection rates and effectiveness of 18f-fluorodeoxyglucose positron emission tomography (fdg-pet) cancer screening program for prostate cancer in japan, which is defined as a cancer-screening program for subjects without known cancer. it contains fdg-pet aimed at detection of cancer at an early stage with or without additional screening tests ...

background: to retrospectively describe imaging characteristics of liver metastases on fused fdg-pet/ mri data sets and to compare the diagnostic accuracy of mri and fused fdg-pet/mri data sets for the detection of liver metastases in patients undergoing systemic anticancer treatment. materials and methods: 43 oncological patients (mean age: 56+/- 11 years) were investigated by fdg-pet/ct and l...