OBJECTIVE A common complaint for children with pervasive developmental disorder (PDD) is hyperactivity. The purpose of this pilot study was to gather preliminary information on the efficacy of guanfacine in children with PDD and hyperactivity. METHODS Children with PDD accompanied by hyperactivity entered the open-label trial if there was a recent history of failed treatment with methylphenid...

Due to co-morbidities and treatment resistant nature of pervasive developmental disorder (PDD), diverse combinations of regimens have been tried. This retrospective study aimed to explore adjunctive use of aripiprazole in children with PDD. Changes in illness severity were measured by Clinical Global Impression of Severity (CGI-S) and Clinical Global Impression of Improvement (CGI-I) in 14 arip...

OBJECTIVE Changes in autism diagnostic criteria found in DSM-5 may affect autism spectrum disorder (ASD) prevalence, research findings, diagnostic processes, and eligibility for clinical and other services. Using our published, total-population Korean prevalence data, we compute DSM-5 ASD and social communication disorder (SCD) prevalence and compare them with DSM-IV pervasive developmental dis...

Pervasive Developmental Disorder (PDD) is a complex psychiatric diagnostic category encompassing five diagnoses. Children diagnosed within this category present with an incredibly varied picture of skills, abilities, and limitations and may require nontraditional educational approaches, a variety of scaffolding supports, and alternative interventions. To promote the child’s development and comp...

Controlling the symptoms that are characteristic of patients with pervasive developmental disorders is often challenging. We report on the safety and efficacy of olanzapine in the treatment of 7 patients with pervasive developmental disorders. The patients were all male and ranged in age from 8 to 52 years. They received olanzapine doses of 5-10 mg/d along with their various other drug regimens...

children with autism spectrum disorders (asds) have great problems in social interactions including face recognition. there are many studies reporting deficits in face memory in individuals with asds. on the other hand, some studies indicate that this kind of memory is intact in this group. in the present study, delayed face recognition has been investigated in children and adolescents with asd...

OBJECTIVE To investigate the efficacy and safety of risperidone for the treatment of disruptive behavioral symptoms in children with autism and other pervasive developmental disorders (PDD). METHODS In this 8-week, randomized, double-blind, placebo-controlled trial, risperidone/placebo solution (0.01-0.06 mg/kg/day) was administered to 79 children who were aged 5 to 12 years and had PDD. Beha...

Elizabeth R. Blum and Rajesh K. Kana (University of Alabama at Birmingham): Conceptual Issues in Psychiatric Disorders: The Curious Case of Autism [email protected] According to the DSM-IV, autism is a developmental disorder characterized by impairments in reciprocal social interaction, language, and communication; restricted interests; and repetitive behaviors. Despite being the subject of active ...

OBJECTIVES Increasing numbers of young children referred for a differential diagnosis of autism spectrum disorders (ASD) necessitates better understanding of the early syndrome expression and the utility of the existing state-of-the art diagnostic methods in this population. METHOD Out of 31 infants under the age of 2 years referred for a differential diagnosis, 19 were diagnosed with autism,...

The utility of the developmental quotient (DQ) obtained with the Psychoeducational Profile Revised (PEP-R) was assessed as a means of estimating cognitive ability in young children with pervasive developmental disorders. Data from the PEP-R were analysed in a sample of 44 children aged from 2.0 to 5.9 years (mean 3.46 ± 1), 13 with an autistic disorder and 31 with a pervasive developmental diso...