AIMS Pulmonary vein (PV) stenosis has been described as a complication after catheter ablation of atrial fibrillation. The aim of the study was to investigate the diagnostic role of transesophageal echocardiography (TEE) in the assessment of PV stenosis. METHODS Ninety-one patients (71 men, mean age 57+/-16years), initially treated by catheter ablation of atrial fibrillation, underwent re-abl...

Parvalbumin (PV)-expressing inhibitory interneurons are the most numerous GABAergic interneuron type in the neocortex and hippocampus (HPC). Selective reductions in PV interneurons are observed in cortical and limbic regions in postmortem human schizophrenic brain tissue. Reductions in PV expression are also observed in rodents following acute and/or chronic treatment with NMDAantagonists (e.g....

BACKGROUND The mechanism of pulmonary vein (PV) triggers of atrial fibrillation remains unclear. We performed adenosine (ADO) testing after PV isolation to characterize spontaneous dissociated PV rhythm and ADO-induced PV ectopy. METHODS AND RESULTS Seventy-four patients (61 men; age, 61±10 years) undergoing PV isolation for atrial fibrillation were studied. For each isolated PV, dissociated ...

In the hippocampus, the calcium-binding protein parvalbumin (PV) is expressed in interneurons that innervate perisomatic regions. PV in GABAergic synaptic terminals was proposed to limit repetitive GABA release by buffering of "residual calcium." We assessed the role of presynaptic PV in Ca(2+)-dependent GABA release in the hippocampus of PV-deficient (PV-/-) mice and wild-type (PV+/+) litterma...

We discuss the problem of construction of inference procedures which can manipulate with uncertainties measured in ordinal scales and fulfil to the property of strict monotonic­ ity of conclusion. The class of A-valuations of plausibility is considered where operations based only on information about linear or­ dering of plausibility values are used. In this class the modus ponens generating fu...

Radiofrequency catheter ablation of atrial fibrillation (AF) is an effective rhythm control strategy, and its efficacy has been proved to be superior to anti-arrhythmic drugs.1-3) Recently, the European Society of Cardiology’s 2010 revised guidelines for AF management suggested catheter ablation as the firstline treatment in patients with paroxysmal lone AF.4) When Haissaguerre et al.5) initial...

Mutations in the thyroid hormone receptor beta (TRbeta) gene result in resistance to thyroid hormone. However, it is unknown whether mutations in the TRalpha gene could lead to a similar disease. To address this question, we prepared mutant mice by targeting mutant thyroid hormone receptor kindred PV (PV) mutation to the TRalpha gene locus by means of homologous recombination (TRalpha1PV mice)....

INTRODUCTION The significance of intermittent tachycardia within a pulmonary vein (PV) during an episode of atrial fibrillation (AF) is unclear. The aim of this study was to determine the role that intermittent PV tachycardias play in AF. METHODS AND RESULTS In 56 patients with AF, segmental ostial ablation guided by PV potentials was performed to isolate the PVs. The characteristics of inter...