B striato-pallido-dentate calcinosis (Fahr’s disease) is known as bilateral symmetric calcification, mainly of the basal ganglia and the dentate nucleus of the cerebellum.1 The clinical features can be varied. The diagnosis is established by CT or MRI of brain and ruling out calcium metabolism abnormalities and developmental defects. Restless legs syndrome (RLS) is a common neurological sensori...

Stiff-person syndrome (SPS) is a disorder characterized by progressive muscle rigidity with superimposed painful muscle spasms and gait impairment due to continuous motor activity. Evidence has accumulated in favor of SPS representing an autoimmune, predominantly encephalomyelopathic disorder resulting from B-cell-mediated clonal production of autoantibodies against presynaptic inhibitory epito...

A 37-year-old man was admitted to our hospital in 1998 with severe contraction of both masseter muscles, which made him unable to open his mouth. He could only drink using a straw fitting through a tooth gap. Spasms of the facial and masseter muscles had started in 1993 and transiently improved after treatment with benzodiazepines. The patient’s history included treatment of back and joint pain...

Background: Patients with stiff-person syndrome (SPS) have circulating antibodies against glutamic acid decarboxylase, the rate-limiting enzyme responsible for the synthesis of -aminobutyric acid (GABA). Although the patients’ symptoms of stiffness and unexpected spasms can be explained on the basis of reduced or impaired inhibitory neurotransmitters, such as GABA, it is unclear whether the lev...

Introduction: Stiff-person syndrome (SPS) is a rare autoimmune neurological disorder presenting with inability to perform daily activities independently. Because SPS is a rare disorder, the efficacy of physiotherapy in the management of SPS is not yet known. Case Presentation: The patient was a 65-year-old female with SPS diagnosed 1 year before. Assessments were performed, such as range of mot...

Eponymic terms or eponyms are labels describing phenomena that reflect the name(s) of the person(s) who first described the phenomena. Using a similar term to describe different forms of pathology leads to a muddle. In this paper, we describe "Clerambault's syndrome" and "Kandinsky-Clerambault's syndrome" and discuss and clarify the confusion surrounding these different syndromes.

2006;132:196-197 J Thorac Cardiovasc Surg Tsukioka and Shigefumi Suehiro Takashi Iwata, Kiyotoshi Inoue, Shinjiro Mizuguchi, Ryuhei Morita, Takuma thymoma Thymectomy for paraneoplastic stiff-person syndrome associated with invasive http://jtcs.ctsnetjournals.org/cgi/content/full/132/1/196 located on the World Wide Web at: The online version of this article, along with updated information and se...

[This corrects the article on p. e281 in vol. 3, PMID: 27606356.].

Stiff-person syndrome (SPS) is an autoimmune neurological disorder characterized by rigidity of the trunk and proximal limb muscles, intermittent superimposed spasms, and increased sensitivity to external stimuli. It has been more than 50 years since Moerch and Woltman reported the first 14 cases with this syndrome. During the last half century, many autoantibodies discovered, such as anti-glut...