The precise physiological role of acetylcholine in synaptic transmission in the insect central nervous system has been a subject of some speculation and controversy. One of the main difficulties involved in postulating the existence of a conventional cholinergic system in the insect central nervous system has been the relative insensitivity of intact ganglia to applied acetylcholine solutions (...

Oxazosulfyl is the first representative of a novel sulfyl class insecticides with potent and cross-spectrum insecticidal activity, albeit an unclear mechanism action. As potential agent pest control in rice fields, we investigated action oxazosulfyl on nervous system voltage-gated sodium channels insects. After injection 10 μg oxazosulfyl, American cockroaches (Periplaneta americana) were quick...