Background: The major immuno-modulating effects of Ganoderma lucidum include mitogenicity and activation of immune effector cells such as T cells, macrophages and natural killer cells resulting in the production of cytokines. Objective: The purpose of this study was to evaluate the expression of CD40 and CD80 by G. lucidum-treated human peripheral blood mononuclear cells. Methods: Monocytes wer...

Here we describe the generation of induced pluripotent stem cell lines from each member - male proband, mother, father a schizophrenia case-parent trio that participated in an exome sequencing study, and 3 de novo mutations were identified proband. Peripheral blood mononuclear cells obtained all three individuals reprogrammed using Sendai virus particles carrying Yamanaka transgenes. These iPSC...

results the median level of pbmcs htert mrna in survivors increased with treatment time and was significantly higher than the corresponding level in non-survivors after 14 days of treatment (p < 0.001). subgroup analyses showed that the levels of pbmcs htert mrna were remarkably higher in patients with acute-on-chronic liver failure than in those with chronic liver failure (p < 0.05). in patien...