Cartilage has poor regenerative capacity. Donor site morbidity and interference with joint homeostasis should be considered when applying the autologous chondrocyte transplantation technique. The use of ectopically produced cartilage, derived from periosteum, might be a novel method to heal cartilage defects. Ectopic cartilage was produced by dissecting a piece of periosteum from the tibia of r...

BACKGROUND Although autologous chondrocyte implantation (ACI) is a well-established therapy for the treatment of isolated cartilage defects of the knee joint, little is known about typical complications and their treatment after ACI. HYPOTHESIS Unsatisfactory outcome after ACI is associated with technique-related typical complications. STUDY DESIGN Case series; Level of evidence, 4. METHO...

A case is presented which is thought to be the first described example of heterotopic ossification occurring within the path of a bullet. Although the information was not available from prior medical records, the bullet presumably passed though bone or periosteum, thereby seeding the permanent cavity and facilitating ossification within the surrounding muscle and soft tissue.

Lewis433 demonstrated that stimulation of "myofacial" structures, i.e., muscle, periosteum, and ligaments, cause pain quite similar to visceral pain. Lewis433 stimulated referred pain in 94% of experimental injection of 6% normal saline into deep skeletal structures of 28 normal volunteers. The pattern of referred pain was quite consistent, although not confined to the injected dermatomal segment.

Pain is associated with most bony pathologies. Clinical and experimental observations suggest that bone pain can be derived from noxious stimulation of the periosteum or bone marrow. Sensory neurons are known to innervate the periosteum and marrow cavity, and most of these have a morphology and molecular phenotype consistent with a role in nociception. However, little is known about the physiol...

Intraarticular distal humerus fractures occur in adolescents and represent a unique morphology that is amenable to different surgical techniques than adults or younger children, especially when one column remains intact. Despite articular involvement, minimally invasive approach utilizing the intact periosteum opposing of bone can often achieve successful reduction fixation. Here, we present an...