This article reviews how menopause and age related hormonal bone changes effect periodontal healing. After menopause, with the cessation of ovarian estrogen production and its bone protecting effects, women become more susceptible to periodontal disease and tooth loss. The inflammatory processes involved in osteoporosis and periodontal disease will be reviewed. Estrogen deficiency results in up...

When dealing with patients with periodontal disease of variable severities, dentists must often choose between treating and restoring the involved tooth or indicating its extraction. Different criteria have been adopted in this decision-making process. The purpose of this study was to evaluate the criteria adopted by dentists to indicate the extraction of teeth with periodontitis. Dentists were...

C-telopeptides and related pyridinoline cross-links of bone Type I collagen are sensitive markers of bone resorption in osteolytic diseases such as osteoporosis and osteoarthritis. We have studied the release of C-telopeptide pyridinoline crosslinks of Type I collagen as measures of bone destruction in periodontal disease. Studies in preclinical animal models and humans have demonstrated the re...

Although periodontal diseases are initiated by bacteria that colonize the tooth surface and gingival sulcus, the host response is believed to play an essential role in the breakdown of connective tissue and bone, key features of the disease process. An intermediate mechanism that lies between bacterial stimulation and tissue destruction is the production of cytokines, which stimulates inflammat...

Last year, the American Association of Orthodontists (AAO) Board of Trustees appointed President Lee Graber and me to a joint task force along with the current president of the American Academy of Periodontology and another practicing periodontist. Our charge was to determine how orthodontists can avoid being sued for periodontal problems that arise during orthodontic treatment. Is this a real ...

Alveolar bone loss is a hallmark of periodontitis progression and its prevention is a key clinical challenge in periodontal disease treatment. Bone destruction is mediated by the host immune and inflammatory response to the microbial challenge. However, the mechanisms by which the local immune response against periodontopathic bacteria disturbs the homeostatic balance of bone formation and reso...

Introduction Periodontal diseases(PD) are mainly associated with gram negative bacteria that initiate a series of events leading to the loss of periodontal attachment and alveolar bone surrounding teeth. Porphyromonas gingivalis (Pg) is considered to be one of the most important oral cavity infectious agents in adults patients. Pg is uncommon or found in low numbers in healthy children and don’...

More than 700 bacterial species are able to colonize the subgingival periodontal pocket of humans. Periodontitis is a multi-factorial chronic inflammatory disease of the periodontium with varying degrees of bone loss. Destruction of periodontium starts by colonization of gram-negative anaerobic microorganisms. Several methods have been used for identifying the involved species. The aim of this ...

Background– Periodontal disease, if not interfered, will headway further with attachment loss involving the bifurcation or trifurcation of multirooted teeth. Furcation involved molar teeth respond less favorably to conventional periodontal therapy alone resulting into tooth loss. Combining osseous grafting guided tissue regeneration membrane may enhance response treatment as compared graft – on...

background: corticosteroids (cs) are used widely for their anti-inflammatory and immunosuppressive properties. they have the potential to cause dramatic improvement as well as produce equally dramatic adverse effects. the clinical misuse like over prescription of the drug should be avoided. long-term administration may cause many adverse effects leading to impaired oral health. oral health is u...