BACKGROUND: The objective was to determine the incidence of, and factors associated with contralateral neck failure (CNF) in oral tongue squamous cell carcinoma (OTSCC). METHODS: Consecutive patients OTSCC between 2007 2016 were included. predefined policy of included dissection (ND) where primary tumor extended/crossed midline or involved; elective nodal irradiation (ENI) ≤1 cm from midline/2 ...

Back Ground:The most important prognostic factor for squamous cell carcinoma (SCC) of oral is the status cervical lymph nodes. Cure rates drop by 50% with involvement regional nodes.The rate occult metastasis in clinically negative neck tongue cancers ranges from <20% to >30% depending on many predictors. Methods:The relationship clinical and histologic features primary tumor nodes was in...

PURPOSE Perineural invasion (PNI) by cancer cells is an ominous clinical event that is associated with increased local recurrence and poor prognosis. Although radiation therapy (RT) may be delivered along the course of an invaded nerve, the mechanisms through which radiation may potentially control PNI remain undefined. EXPERIMENTAL DESIGN An in vitro co-culture system of dorsal root ganglia ...

OBJECTIVE To determine the relationship between perineural invasion (PNI) on prostate biopsy and radical prostatectomy (RP) outcomes in a contemporary RP series, as there is conflicting evidence on the prognostic significance of PNI in prostate needle biopsy specimens. PATIENTS AND METHODS From 2002 to 2007, 1256 men had RP by one surgeon. Multivariable logistic regression and Cox proportiona...

Figure 1. Right lower back lesion diagnosed as squamous cell carcinoma on previous shave biopsy with final excisional biopsy results of squamoid ductal eccrine carcinoma. DESCRIPTION An 89-year-old man presented with a rapidly progressing lesion of the right lower back initially diagnosed as squamous cell carcinoma (SCC). Excisional biopsy showed primary squamoid eccrine ductal carcinoma (SEDC)...

RATIONALE Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs. PATIENT CONCERNS We report the case of a 59-year-old woman who presented with Garcin syndrome, which gradually progressed over a period of 2 years. DIAGNOSIS A left parotid gland...

Cutaneous adenoid cystic carcinoma (CACC) is an extremely rare neoplasm of head and neck region, and is characterized by propensity for local recurrence and perineural invasion. Late distant metastases occur usually to lungs. Although patients with lung metastases from CACC cannot be cured, long-term survival may be possible due to its slow-growing malignancy. We report a case of a 69-year-old ...

tumor angiogenesis shown by microvessel count (mvc) or microvessel density (mvd), is assessed by several studies as prognostic factor in some types of tumors, and also in colorectal carcinoma. this article is payed to correlation between clincopathologic factors and tumor angiogenesis. in this study, immunohistochemical techniques are used for vascular evaluation in specimens from twenty-nine c...