Nasal septal perforation has been well recognized in patients with various rheumatic diseases. To our knowledge, this condition has not been reported in children with systemic juvenile idiopathic arthritis (SJIA) or patients with adult onset Still's disease (AOSD). We describe 3 patients with persistent SJIA/AOSD who developed nasal septal perforation during the course of their disease. As illu...

Tooth root perforation is an artificial communication between the oral environment and the supporting structures in the external root surfaces which may causes serious implications that can even lead to extraction, however if diagnosed early and with appropriate management of the perforation will lead to long term survival of the tooth. A PubMed search was carried out of which 121 results were ...

The endoscopic placement of biliary stents for benign and malignant biliary disease has been performed for over a decade. Several complications of stent placement have been described such as pancreatitis, hemorrhage, cholangitis, and perforation. Migration of biliary stents is a rare event, which can cause severe complications such as gastrointestinal tract perforation. We report the case of a ...

Neonatal colonic perforation is a rarely seen condition. Plain abdominal radiography of a 28-hour newborn consulted for vomiting and bloody stool revealed the presence of subdiaphragmatic free air, which necessitated surgical exploration. Transverse colonic perforation was detected during the exploration, and subsequently, a colostomy and appendectomy were performed. The postoperative follow-up...

BACKGROUND Peritonitis secondary to small bowel perforation is a common surgical emergency seen across the globe. METHODS A young male patient presented with ileal perforation that was repaired primarily. He recovered uneventfully after the operation. RESULTS Histopathology of the margins of the perforation revealed tuberculosis. A search for evidence of a primary focus of tuberculosis was ...

In patients with malignancy who receive aflibercept based chemotherapy, gastrointestinal perforation is among the reported adverse events with a prevalence of 1.9%. This complication may lead to mortality up to 10.8%. We here report a case of small bowel perforation that occurred fifteen days after the first cycle of aflibercept in a 58-year old female who had metachronous colorectal liver meta...

BACKGROUND Spontaneous intestinal perforation of the extremely low birth weight infant (< or = 1000 g) is associated with a high incidence of Candida and coagulase-negative Staphylococcus sepsis. Little is known about prenatal risk factors, and histopathologic examination of placentas in infants with spontaneous intestinal perforation has not been reported. OBJECTIVES Our objective was to inv...

BACKGROUND The purpose of this study was to examine factors that could help reduce primary perforation during insertion of a framed intrauterine device (IUD) and to determine factors that contribute in generating enough uterine muscle force to cause embedment and secondary perforation of an IUD. The objective was also to evaluate the main underlying mechanism of IUD expulsion. METHODS We comp...

Hypopharyngeal perforation following minor trauma: a case report and literature review c A rare complication of non-penetrating blunt neck trauma, hypopharyngeal perforation is mainly reported in association with high velocity road traffic accidents. The proposed injury mechanism is neck hyperextension associated with airway closure due to cervical compression against the steering wheel. Low ve...

Cytomegalovirus (CMV)-induced colitis is a severe inflammatory reaction of the colon as a result of CMV infection. It typically presents in immunocompromised patients as a reactivated latent infection. Complications include toxic megacolon, necrotizing colitis, peritonitis, and sepsis. Colonic perforation may also result from the inflammation and ischemic injury, but it is exceedingly rare. We ...