In recent years, peptides have spurred increased interest as one of the most important classes bioactive food components [...]

Intercellular signaling events mediated by neuropeptides and peptide hormones represent important targets for both basic science drug discovery. For many bioactive peptides, the protein receptors that transmit information across receiving cell membrane are not known, severely limiting these pathways as potential therapeutic targets. Identifying receptor(s) a given of interest is complicated sev...

• Designed peptides showed a link between catalytic amino acids order and activity. Side chains engaged in stabilizing may become inaccessible to catalysis. Structural characterizations do provide insights on catalysis by peptide assemblies. Amphiphilic that induce are interesting alternatives natural enzymes thanks robustness of their synthesis the ability certain types conformations specific ...