We have developed a pen and writing tablet for use by subjects during fMRI scanning. The pen consists of two jacketed, multi-mode optical fibers routed to the tip of a hollowed-out ball-point pen. The pen has been further modified by addition of a plastic plate to maintain a perpendicular pen-tablet orientation. The tablet is simply a non-metallic frame holding a paper print of continuously var...

This study is conducted to investigate efficacy of an insulin jet injector and an insulin pen in treatment of type 2 diabetic patients. Sixty patients with type 2 diabetes were treated with rapid-acting insulin (regular insulin) and insulin analog (insulin aspart) using the jet injector and the pen in 4 successive test cycles. Postprandial glucose and insulin concentrations in blood were measur...

This thesis presents new contributions to the area of pen-based interfaces for 3D shape modeling: (1) a simple but efficient algorithm for segmenting markings of pen input, (2) an interaction framework for pen-based applications, and (3) based on these two, a new 3D modeling environment. The segmentation of pen markings is a hidden difficulty in the development of a penbased application. It is ...

This paper proposes a advance technology which is completely innovative and creative. The urge of inventing this proposal lies on the bases of the idea of making a pen drive have an extendable memory capacity with a modern and digitalized look. This device can operate without the use of a computer system or a mobile. The computerized pen drive has a display unit to display the contents of the p...

BACKGROUND The accurate detection of approximal caries is generally difficult. The aim of this study was to assess the ability of the pen-type laser fluorescence device (LF pen) to detect approximal carious lesions in comparison to bitewing radiographs (BW). METHODS Three hundred forty-one tooth surfaces were diagnosed in 20 patients with an average age of 26.70 (±2.82) years. Each test tooth...

In the title complex, [Ni(C(7)H(4)NO(3)S)(2)(C(3)H(10)N(2))(2)] or [Ni(sac)(2)(pen)(2)] (sac = saccharinate or 1,1,3-trioxo-2,3-dihydro-1λ(6,2)-benzothia-zol-2-ide and pen = propane-1,3-diamine), the Ni(II) ion sits on an inversion center, being coordinated by two N atoms of the sac ligands, which occupy trans positions, and four N atoms of the bidentate pen ligands to define a distorted octa-h...

This paper presents an accelerometer-based pen device for online handwriting recognition applications. The accelerometer-based pen device consists of a triaxial accelerometer, a microcontroller, and an RF wireless transmission module. Users can hold the pen device to write numerals in air without space limitations. The accelerations generated by hand motions are generated by the accelerometer e...

In the fungus Penicillium chrysogenum, penicillin (PEN) production is compartmentalized in the cytosol and in peroxisomes. Here we show that intact peroxisomes that contain the two final enzymes of PEN biosynthesis, acyl coenzyme A (CoA):6-amino penicillanic acid acyltransferase (AT) as well as the side-chain precursor activation enzyme phenylacetyl CoA ligase (PCL), are crucial for efficient P...

Drawings made with precise pen strokes accurately reveal the geometric forms that give subjects their characteristic shape. We present a system for non-photorealistic rendering of precise drawing strokes over dense 3D triangle meshes with arbitrary topology. During an automatic pre-process, we construct an extended version of the edge-buffer data structure to allow the calculation of shape meas...