نتایج جستجو برای: pediatric lupus
تعداد نتایج: 159355 فیلتر نتایج به سال:
ساختار ژنتیکی جمعیت گرگ در سطح دنیا تحت تأثیر وقوع تجزیه شدن جمعیت و نوسان های جمعیتی در طی دوره های یخبندان قرار گرفته است. با توجه به پراکندگی گسترده گرگ در ایران و نیاز به شناسایی دقیق گونه ها در برنامه های حفاطتی، در این مطالعه جایگاه و روابط زیرگونه های احتمالی گرگ در ایران canis lupus pallipes، canis lupus cubanensis و canis lupus lupus با سایر زیرگونه های موجود در دنیا، بر اساس توالی کام...
UNLABELLED BACKGROUND A high prevalence of autoimmune disease (AD) has been documented in relatives of adult patients with systemic lupus erythematosus (SLE). However, data on familial inheritance patterns in pediatric SLE patients is scarce. FINDINGS The charts of 69 patients with pediatric-onset SLE were reviewed retrospectively. The primary aim was to describe the prevalence and types o...
Background & Objective: Systemic lupus erythematosus (SLE) is a disease with life-threatening complications. Since evidence indicates that measurement of triglyceride (TG) and HDL levels and tumor necrosis α factor (TNF- α) and its types I and II soluble receptors plays a major role in evaluation of lupus activity, this study was conducted to investigate the relationship between the above menti...
Inflammatory myositis is reported in 4-16% of adult systemic lupus erythematosus (SLE) patients. The aim of this study was to determine the prevalence of myositis in a cohort of pediatric SLE patients in the southeastern United States. A retrospective chart review was performed of 55 SLE patients evaluated by Pediatric Rheumatologists in Alabama since January 1, 2008. Patients were defined as h...
STUDY DESIGN Resident's case problem. BACKGROUND In the United States, minocycline is a frequently prescribed medication for the treatment of moderate to severe acne, a common condition in adolescents. The use of minocycline has been associated with severe adverse effects that frequently comprise a musculoskeletal component, including drug-induced lupus. Physical therapists have the responsib...
BACKGROUND North American pediatric rheumatologists have created an investigator-initiated research network (the Childhood Arthritis and Rheumatology Research Alliance - CARRA) to facilitate multi-centre studies. One of the first projects undertaken by this network was to define, by consensus, research priorities for the group, and if possible a first group-sponsored clinical trial in which all...
OBJECTIVE To compare health care use and costs for youth with chronic health conditions before and after transfer from pediatric to adult health care services. METHODS Youth born in Ontario, Canada, between April 1, 1989, and April 1, 1993, were assigned to 11 mutually exclusive, hierarchically arranged clinical groupings, including "complex" chronic conditions (CCCs), non-complex chronic con...
The antiphospholipid syndrome (APS) is recognized increasingly as the most common acquired hypercoagulation state of autoimmune etiology and may occur as an isolated clinical entity (primary APS) or in association with an underlying systemic disease, particularly systemic lupus erythematosus (SLE). The major differences between pediatric and adult APS include absence of common acquired risk fac...
BACKGROUND Rheumatic diseases in children are associated with significant morbidity and poor health-related quality of life (HRQOL). There is no health-related quality of life (HRQOL) scale available specifically for children with less common rheumatic diseases. These diseases share several features with systemic lupus erythematosus (SLE) such as their chronic episodic nature, multi-systemic in...
The proven effectiveness of biologics and other immunomodulatory products in inflammatory rheumatic diseases has resulted in their widespread use as well as reports of potential short- and long-term complications such as infection and malignancy. These complications are especially worrisome in children who often have serial exposures to multiple immunomodulatory products. Post-marketing surveil...
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