background: early diagnosis of brain tumors has significant effect on the treatment process. brain metastatic tumors are usually diagnosed following the neurological symptoms in patients or incidentally after computerized tomography (ct) scan and magnetic resonance imaging (mri) requests of the brain. objectives: implementation of a new method for being informed about the origin of brain tumors...

OBJECTIVES To estimate survival and evaluate prognostic factors of pediatric patients with central nervous system (CNS) tumors treated in a single center. METHODS Retrospective analysis of survival of 103 children with primary brain tumors diagnosed consecutively from January 2000 to December 2006. Cox regression was used for multivariate analysis of factors that affect overall survival to de...

Epilepsy surgery is common in the face of benign brain tumors, but rarely for patients with a history of malignant brain tumors. Seizures are a common sequelae in survivors of malignant pediatric brain tumors. Medical management alone may not adequately treat epilepsy, including in this group. We report four cases of patients who previously underwent gross total resection, radiation therapy, an...

OBJECTIVE The objective of present study was to observe the histopathological pattern of intracranial tumors in children (< 15 yrs) and to correlate the site of lesion along with the histological diagnosis. SETTING The study included consecutive cases of intracranial tumors diagnosed in children (< 15 yrs.) in the section of histopathology at the Aga Khan University Hospital, Karachi during t...

purpose: to evaluate of proton therapy (pt) for neurosurgery patients and is also to explain the need for this system in iran. methods: a literature review was conducted (1984–2016). the strategy included a combination of keywords including proton therapy, neck, neurosurgery, brain, head, tumor, spine, arteriovenous malformation (avms), cervical and spine in database of pubmed. new generation p...

Abstract INTRODUCTION T cell dysfunction contributes to immune escape in patients with cancer and is particularly severe CNS tumors. sequestration a contributing mechanism of lymphopenia lymphoid organ contraction occurring treatment naive mice Glioblastoma. Our group demonstrated that this phenomenon mediated by loss S1P1 surface expression on T-Cells within the bone marrow. We murine models r...

A recent study found that a majority of pediatric patients diagnosed with central nervous system primitive neuroectodermal tumors may have other types of central nervous system cancers instead. Researchers also concluded that these rare brain tumors fall into four distinct molecular subtypes. The findings may lead to more accurate diagnoses and more-tailored treatment plans.

BACKGROUND AND PURPOSE Neurointerventions in children have dramatically improved the clinical outlook for patients with previously intractable cerebrovascular conditions, such as vein of Galen malformations and complex arteriovenous fistulas. However, these complex and sometimes lengthy procedures are performed under fluoroscopic guidance and thus unavoidably expose vulnerable pediatric patient...