Centrosomes comprise a pair of centrioles surrounded by a matrix of pericentriolar material (PCM). In vertebrate cells, Pericentrin plays an important part in mitotic PCM assembly, but the Drosophila Pericentrin-like protein (PLP) appears to have a more minor role in mitotic fly cells. Here we investigate the function of PLP during the rapid mitotic cycles of the early Drosophila embryo. Unexpe...

IgM plasma cell myeloma (PCM) is a rare entity, and CD19 positivity is found in only 1-4% of PCM. Here we report a unique case of IgM PCM, in which the plasma cells are positive for CD19. Clinically, the patient presented with hyperviscosity syndrome, mimicking the clinical manifestation of Waldenstrom's macroglobulinemia. In addition, the IgM para-protein from the patient behaved like cryoglob...

Phase-change materials (PCM) can be used to reduce thermal stress and improve thermal comfort for workers wearing protective clothing. The aim of this study was to investigate the effect of PCM in protective clothing used in simulated work situations. We hypothesized that it would be possible to optimize cooling performance with a design that focuses on careful positioning of PCM, minimizing to...

Separating digestive and urinary outlets is a critical step during mammalian embryogenesis. However, the natural history of these structures is poorly studied, and little is known about their embryonic origin. Here, we show that peri-cloacal mesenchymal (PCM) progenitors are the major source of these structures. Surprisingly, PCM progenitors also contribute to perineum, a structural barrier sep...

This paper presents experimental results that can be applied to select a possible phase change material (PCM), such as a latent heat material (LHM), to control the hydration heat in mass concrete structures. Five experimental tests (microconduction, simplified adiabatic temperature rise, heat, and compressive strength tests) were conducted to select the most desirable LHM out of seven types of ...

Many cells express a membrane-coupled external mechanical layer, the pericellular matrix (PCM), which often contains long-chain polymers. Its role and properties are not entirely known, but its functions are believed to include physical protection, mechanosensing, chemical signalling or lubrication. The viscoelastic response of the PCM, with polysaccharides as the main structural components, is...

There are several emerging memory technologies looming on the horizon to compensate the physical scaling challenges of DRAM. Phase change memory (PCM) is one of such candidates proposed for being part of the main memory in computing systems. One salient feature of PCM is its multi-level cell (MLC) property which can be used to multiply the memory capacity at the cell level. However, due to the ...

passive solar systems such as solar chimneys need solar radiation in order to work. therefore, they cannot present stable natural ventilation when solar energy vanishes: to have a more robust and stable condition, solar energy should be stored during the day and released back during the night. phase change materials can save additional thermal energy during the day and release it during the nig...

For the past few decades, analog voiceband modems have been used extensively to carry digital information over the Public Switched Telephone Network (PSTN). Conventional voiceband modems treat the PSTN as an analog communication channel. However, today’s PSTN is mostly a digital network except for the basic telephone services provided via analog subscriber lines. The conventional model of analo...

Dear Editor CML and plasma cell myeloma (PCM) arise from pluripotent stem cells and lymphoid cells, respectively [1]. Since different cell lines give rise to CML and PCM, development of both malignancies in one patient is uncommon; only 17 such cases have been reported worldwide [2-5]. Here, we attempt to address questions about the mechanisms of co-existence of these two diseases. A 76-yr-old ...