A study of mean birth weight, small-for-gestational-age infants, and preterm birth was conducted at the US Marine Corps Base at Camp Lejeune, North Carolina, where drinking water was contaminated with volatile organic compounds. Tetrachloroethylene (PCE) was the predominant contaminant. The authors used multiple linear and logistic regression to analyze 1968-1985 data from 11,798 birth certific...

OBJECTIVES To evaluate a spectrophotometric field kit (Test-Mate-OP) for repeatability and validity in comparison with reference laboratory methods and to model its anticipated sensitivity and specificity based on these findings. METHODS 76 farm workers between the age of 20 and 55, of whom 30 were pesticide applicators exposed to a range of organophosphates in the preceding 10 days, had bloo...

Tetrachloroethylene (PCE) is one of the most frequently detected volatile organic compounds (VOCs) in water systems across the USA. In New Jersey, the Department of Environmental Protection (NJDEP) monitors surface water quality at several sites throughout the state. However due to budget and scientific limitations, the sampling data is insufficient to assess all river streams in New Jersey. To...

Tetrachloroethene (PCE) dehalorespiration was investigated in a continuous coculture of the sulfate-reducing bacterium Desulfovibrio fructosivorans and the dehalorespiring Desulfitobacterium frappieri TCE1 at different sulfate concentrations and in the absence of sulfate. Fructose (2.5 mM) was the single electron donor, which could be used only by the sulfate reducer. With 2.5 mM sulfate, the d...

An experimental demonstration of active stateful PCE for flexgrid networks is presented. The PCE enables elastic operations on established connections and, when required, performs hitless defragmentation of spectrum resources. Experimental assessment, including shifting of 400Gbps four sub-carrier superchannel is shown.

It has taken three decades from the first report of microbial polychlorinated biphenyl (PCB) dechlorination to identify even one of the enzymes responsible. By combining conventional techniques with their own ingenuity, the latest technologies, and a bit of luck, Wang et al., in PNAS, have identified not one, but three distinct enzymes that can reductively dechlorinate PCBs (1). This finding is...

OBJECTIVE To examine the long term effects of prenatal cocaine exposure (PCE) on the language development of 10-year-old children utilizing a prospective design, controlling for confounding drug and environmental factors. PARTICIPANTS Children exposed to cocaine in utero (PCE; n=175) and non-exposed children (NCE; n=175) were followed prospectively to 10years of age and were compared on langu...

PURPOSE The photoreceptor conserved element-1 (PCE-1) sequence is found in the transcriptional regulatory regions of many genes expressed in photoreceptors. The retinal homeobox (Rx or Rax) gene product functions by binding to PCE-1 sites. However, other transcriptional regulators have also been reported to bind to PCE-1. One of these, vsx2, is expressed in retinal progenitor and bipolar cells....

Cellular retinaldehyde-binding protein (CRALBP) is abundantly expressed in the retinal pigment epithelium (RPE) and Muller cells of the retina, where it is thought to function in retinoid metabolism and visual pigment regeneration. Mutations in human CRALBP that destroy retinoid binding have been linked to autosomal recessive retinitis pigmentosa. To identify the DNA elements that regulate expr...