The aim of this study was to investigate the anti-inflammatory property of the ethanol extract of the root and rhizome of Pogostemon cablin (ERP). The anti-inflammatory effect was evaluated using four animal models including xylene-induced mouse ear edema, acetic acid-induced mouse vascular permeability, carrageenan-induced mouse pleurisy, and carrageenan-induced mouse hind paw edema. Results i...

Background: The potential edematogenic effect and the pharmacological characterization of a glucose-mannose-binding lectin from Dioclea violacea (DvL) were investigated. Methods: Paw edema was induced with DvL in control animals, and in animals pretreated with glucocorticoid or with blockers of histamine, nitric oxide synthase, cyclooxygenase, platelet activating factor (PAF), bradykinin and li...

The present study was aimed to the pharmacological screening some traditional Indian medicinal plants for its anti-inflammatory activity. The methanolic and aqueous extracts of leaves of Moringa oleifera and Ocimum gratissimum were taken and evaluated for their anti-inflammatory potential using carrageenan induced hind paw edema method. The methanolic and aqueous extracts of Ocimum gratissimum ...

the present study was designed to assess the cytotoxicity, anti-inflammatory and analgesic properties of methanol extract of woodfordia fruticosa flowers. cytotoxic activity of methanol extract of woodfordia fruticosa flowers was tested using artemia salina (brine shrimp) bioassay. two doses (400 and 600 mg/kg) were evaluated for the anti-inflammatory activity against the carrageenan, histamine...

BACKGROUND Aim of the present study was to evaluate anti-inflammatory activity of newly developed polyherbal formulations DF1911, DF2112 and DF2813. These newly developed formulations are modifications of Dashamoola, a well known Ayurvedic formulation, along with addition of new plants. METHODS Complete Freund's adjuvant (CFA) induced inflammation in rat was used as an experimental model. Eff...

In early studies, we have reported the antinociceptive profile of (-)-spectaline, a piperidine alkaloid from Cassia spectabilis. The present study describes the synthesis, the antinociceptive and anti-inflammatory activities of a series of 2,3,6-trialkyl-piperidine alkaloids: the natural (-)-3-O-acetyl-spectaline (LASSBio-755) and ten semi-synthetic spectaline derivatives. Structure-activity re...

Anti-inflammatory activity of the ethanolic extract of the leaves of Morus indica Linn. was studied in wistar rats using the carrageenan induced left hind paw edema, carrageenan induced pleurisy and cotton pellet induced granuloma model. The ethanolic extract (100 mg/kg, p.o.) inhibited carrageenan induced rat paw edema. It also showed an inhibitory effect on leukocyte migration and a reduction...

Two [Met(0)6]deacetyl-thymosin beta4 analogs containing Phe(4F) or Tyr(Me) at position 12 were synthesized by the manual solid-phase method, and their anti-inflammatory effect on carrageenin-induced edema in the mouse paw was studied. Fluorination of the para-position of Phe12 resulted in a marked antiinflammatory effect on carrageenin-induced edema in the mouse paw compared with that of our sy...

CA Corresponding Author Fax: +81 195 78 3357 E-mail: [email protected] TW O {Met(0)}deacetyl-thymosin b 4 analogs containing Phe(4F) or Tyr(Me) at position 12 were synthesized by the manual solid-phase method, and their anti-inflammatory effect on carrageenin-induced edema in the mouse paw was studied. Fluorination of the para-position of Phe resulted in a marked antiinflammatory effect o...

Sphaeranthus indicus had been widely used for its reported biological activity in indigenous system of medicine. The present investigation was carried out to find the anti-inflammatory effect of ethanolic extract of Sphaeranthus indicus in albino rats. The anti-inflammatory activity was evaluated using acute inflammatory model like carrageenan induced paw edema and chronic inflammatory model li...