During aortic surgery, interruption of spinal cord blood flow might cause spinal cord ischemia-reperfusion injury (IRI). The incidence of spinal cord IRI after aortic surgery is up to 28%, and patients with spinal cord IRI might suffer from postoperative paraplegia or paraparesis. Spinal cord IRI includes two phases. The immediate spinal cord injury is related to acute ischemia. And the delayed...

objectives major differences exist in the anatomy and biomechanics of the growing spine that causes failure patterns different from those in adults. spinal injury in the pediatric patient is a main concern because timely diagnosis and appropriate treatment can prevent further neurologic damage and deformity and potentiate recovery. we conducted a retrospective clinical study of 137 cases (93 bo...

background: recent reports demonstrated that intravenous route as a minimally invasive method, similar to direct injection, is suitable for bone marrow stromal cell (bmsc) transplantation. in this study, we made a comparison of intraspinal and intravenous route of bmsc administration to repair injured spinal cord tissue. methods: six groups of adult female rats were used in this study. laminect...

introduction deep vein thrombosis is one of the most important complications in patients with spinal cord injury. this study compares the effects of mechanical prophylaxis with or without pharmacological prophylaxis on prevention of deep vein thrombosis in patients with spinal cord injury. materials and methods we conducted a double blind clinical trial study with 75 cases. these patients were ...

the case is 43 years old woman referred to emergency department of our hospital with quadriplegia and severe respiratory insufficiency due to c5-c6 injury after falling. she discharged from icu after fixation of the lesion and successful weaning. we evaluated electrical activity of diaphragm signal (edi), respiratory drive (p100) during one month period. we detected increase in level of electri...

OBJECTIVES To study mortality, cause of death and risk indicators for death in Norwegian patients with spinal cord injury. DESIGN A cross-sectional study with retrospective data. SUBJECTS All patients (n=387) with traumatic spinal cord injury admitted to Sunnaas Rehabilitation Hospital, Norway, during the period 1961-82. METHODS Medical records were reviewed retrospectively. Causes of dea...

Huntington’s disease is a neurodegenerative disorder, characterised by progressive cognitive, motor and psychiatric symptoms. Patients with advanced presenting to emergency medical services can pose diagnostic management challenge for physicians unfamiliar the condition. We describe two patients in whom diagnosis of traumatic spinal cord injury was delayed, discuss role that cognitive bias othe...

The degenerative spinal cord disease cervical spondylotic myelopathy (CSM), and caused by trauma, can result in debilitating symptoms affecting quality of life. This study used acupotomy other Korean medicine treatments (acupuncture, herbal medicine, physical therapy) to improve the CSM myelopathy. visual analog scale, modified Japanese Orthopaedic Association scale (mJOA scale), Nurick grading...

Spinal cord injury induces the disruption of blood-spinal cord barrier and triggers a complex array of tissue responses, including endoplasmic reticulum (ER) stress and autophagy. However, the roles of ER stress and autophagy in blood-spinal cord barrier disruption have not been discussed in acute spinal cord trauma. In the present study, we respectively detected the roles of ER stress and auto...

BACKGROUND Spinal cord injury has been reported as a rare complication of spinal cord stimulation (SCS). A review of the literature shows a very low incidence of neurological injury after spinal cord stimulation trial, implantation and revision. The most common reported complication is equipment failure without neurologic injury. The incidence of spinal cord injury after SCS trial, implantation...