This study investigated the effects of dexmedetomidine on heart-type fatty acid binding protein (H-FABP), creatine kinase isoenzymes (CK-MB), and troponin I (cTnI) levels, neurological function and near-term prognosis in patients undergoing heart valve replacement. Patients undergoing heart valve replacement were randomly allocated to remifentanil anesthesia (control group, n=48) or dexmedetomi...

Surgical aortic valve replacement (SAVR) is the only treatment known to improve symptoms and survival in patients with severe, symptomatic aortic stenosis. Perioperative mortality, however, is high among many patients for whom SAVR may be indicated. Percutaneous heart valve replacement (PHVR) is an emerging, catheter-based technology that allows for implantation of a prosthetic valve without op...

Mitral valve leaflet aneurysm is a rare and potentially devastating complication of aortic valve endocarditis. We report the case of a 48-year-old man who had endocarditis of the native aortic valve and a concomitant aneurysm of the anterior mitral valve leaflet. Severe mitral regurgitation occurred after the aneurysm perforated. The patient showed no signs of heart failure and completed a 6-we...

Background/Introduction Logistic EuroSCORE overestimates the risk profile of octogenarians undergoing aortic valve replacement by traditional surgery. EuroSCORE II, that was created in an attempt to improve this previous version, has been evaluated in the general population. However, to our knowledge, there are no studies evaluating the predictive performance of EuroSCORE II in the elderly popu...

FEBRUARY 2004 I ENDOVASCULAR TODAY I 31 D uring the last 2 decades, percutaneous endovascular therapies have revolutionized the treatment of coronary artery disease. However, the development and dissemination of percutaneous approaches to heart valve disease have been less rapid. Whereas rheumatic mitral stenosis and congenital aortic stenosis are effectively managed by balloon valvuloplasty in...

Fifty consecutive patients, 25 undergoing aortic valve replacement and 25 mitral valve replacement, were studied by serial electrocardiography, preoperative and postoperative technetium-99m pyrophosphate radionuclide scanning, and serial measurement of enzymes (creatine kinase, aspartate aminotransferase, urea stable lactic dehydrogenase) and the MB isoenzyme of creatine kinase to define the in...

PATIENTS undergoing replacement of the mitral valve appear to have somewhat less satisfactory early and late results than do those undergoing replacement of the aortic valve, in our experience." 2 Therefore studies were made of the hemodynamic state preoperatively and early postoperatively in patients in whom the Starr-Edwards prosthesis was inserted into the mitral region. The data indicate th...

Method Between January 2008 and December 2009, 200 patients who had undergone a left heart valve replacement were analysed for the degree of TV regurgitation at the end of five years. 162 patients had undergone a Mitral valve surgery and 38 patients had undergone a double valve replacement. Group I 40 patients had a concomitant TV repair (Modified de Vaga’s annuloplasty) during the primary surg...

Transcatheter aortic valve implantation (TAVI) has allowed patients who were previously not fit enough for heart surgery to have a replacement without going through major surgery. Complication rates following TAVI reduced over the last few years, but studies suggest that incidence of several complications remains high. Avoiding is key reducing costs associated with TAVI, which important given p...

Method One hundred and seventy two consecutive patients undergoing aortic valve replacement using the St. Jude Medical Trifecta valve at a single UK centre over a 48-month period were included in this study. Patients undergoing concomitant cardiac procedures were included. All implanted valves were 19, 21, 23, 25, 27 & 29 mm in size. Patients underwent both pre-operative and post-operative tran...