Pasteurella multocida subsp. multocida is a commensal and opportunistic pathogen of food animals, wildlife, and pets and a zoonotic cause of human infection arising from contacts with these animals. Here, an investigation of multiple serotype A strains demonstrated the occurrence of membrane sialyltransferase. Although P. multocida lacks the genes for the two earliest steps in de novo sialic ac...

Bovine respiratory disease (BRD) is the leading cause of significant economic losses in the intensive beef industry worldwide. Beside numerous risk factors Pasteurella multocida, which is regarded as a secondary pathogen, may play a role in the development of the disease. Previous studies of strains from swine pneumonia revealed that there are a few clones associated with clinical disease, sugg...

AIM The aim was to study the bronchoalveolar lavage (BAL) technique in evaluating the local immune response of pig immunized with Pasteurella multocida bacterin vaccine. MATERIALS AND METHODS Weaned piglets were immunized with formalin-inactivated P52 strain of P. multocida bacterin and evaluated for pulmonary immune response in BAL fluid. BAL was performed before vaccination and at different...

Pasteurella multocida is responsible for a wide range of diseases in domestic animals. In rabbits, the agent is related to nasal discharge, pneumonia, otitis media, pyometra, orchitis, abscess, and septicemia. One hundred and forty rabbits with respiratory diseases from four rabbitries in São Paulo State, Brazil were evaluated for the detection of P. multocida in their nasal cavities. A total o...

Pasteurella multocida colonizes animal scratches and bites. This bacterium was described to cause sepsis or endocarditis mainly in immunocompromised patients. We report the case of a 92-year-old woman presenting at the Emergency Department with coma and fever a week after the bite of her cat. The cat bite was misdiagnosed at admission partly due to an underestimation of this event by the patien...

pasteurellosis is one of the important economic diseases in ruminants, especially in cows and buffaloes. it is caused by pasteurella multocida and occasionally by mannheimia haemolytica. the aim of this study was to isolate pasteurella multocida from lungs with probable mentioned bacterial agents in cows and buffaloes in urmia's slaughter house. 240 lung samples over a period of 12 months ...

pasteurellosis is one of the important economic diseases in ruminants, especially in cows and buffaloes. it is caused by pasteurella multocida and occasionally by mannheimia haemolytica. the aim of this study was to isolate pasteurella multocida from lungs with probable mentioned bacterial agents in cows and buffaloes in urmia's slaughter house. 240 lung samples over a period of 12 months were ...

Toxin production and the presence of the toxA gene was assayed in 24 Pasteurella multocida strains isolated from pigs with pneumonia and pleuritis in the State of Rio Grande do Sul, Brazil. Toxigenicity was assessed through a mouse lethality test and a PCR amplification assay was used to obtain a 300 bp product from the toxA gene. In order to demonstrate that the amplified product corresponded ...

The aim of this study was to present the epidemiological, clinical and microbiological data, as well as the management and the outcome of 13 patients with documented Pasteurella multocida infections, diagnosed in the University hospital of Crete, Greece, between 1993 and 2004. Most patients (62%) were >70 years of age. Respiratory tract infections were most commonly encountered (61.5%), followe...

DNA vaccines were constructed with either a 5'-truncated or full-length, genetically detoxified toxin gene from Pasteurella multocida and two different DNA vaccine vectors, distinguished by the presence or absence of a secretion signal sequence. Optimal PMT-specific antibody responses and spleen cell secretion of interferon-gamma following immunization of mice were achieved with pMM4, the const...