Progressive collapse is defined as the spread of an initial damage from one member to another, leading to extensive partial or total collapse of the structure. In this research, the potential of progressive collapse due to a sudden removal of vertical load-bearing elements in reinforced concrete buildings structures with different floor plans such as geometrical regular and irregular floor plan...

Chronic increases in arterial blood flow elicit an adaptive response of the arterial wall, leading to vessel enlargement and reduction in wall shear stress to physiological baseline value. Release of nitric oxide from endothelial cells exposed to excessive shear is a fundamental step in the remodeling process, and potentially triggers a cascade of events, including growth factor induction and m...

The relationship between asymptotic descriptions of vortex–wave interactions and more recent work on ‘exact coherent structures’ is investigated. In recent years immense interest has been focused on so-called self-sustained processes in turbulent shear flows where the importance of waves interacting with streamwise vortex flows has been elucidated in a number of papers. In this paper, it is sho...

Abstract Shear cutting is one of the most widely used manufacturing processes in production sheet metal components. The reasons for this are high output volume combined with low costs per part. profitability process significantly influenced by lifetime active elements and occurrence unexpected disturbances. While there already many publications on former, only few examinations wide spread distu...

We study large-scale dynamo action due to turbulence in the presence of a linear shear flow. Our treatment is quasilinear and equivalent to the standard "first-order smoothing approximation." However it is non perturbative in the shear strength. We first derive an integrodifferential equation for the evolution of the mean magnetic field, by systematic use of the shearing coordinate transformati...

An analytical model of the fluid/cell mechanical interaction was developed. The interfacial shear stress, due to the coupling between the fluid and the cell deformation, was characterized by a new dimensionless number N(fs). For N(fs) above a critical value, the fluid/cell interaction had a damping effect on the interfacial shear stress. Conversely, for N(fs) below this critical value, interfac...

Nanoparticles and microparticles have many potential biomedical applications ranging from imaging to drug delivery. Therefore, in vitro systems that can analyze and optimize the interaction of such particles with cells may be beneficial. Here, we report a microfluidic system that can be used to study these interactions. As a model system, we evaluated the interaction of polymeric nanoparticles ...

Liposomes carrying both recombinant glycoprotein Ia/IIa (rGPIa/IIa) and Ib (rGPIb ) (rGPIa/IIa-Ib -liposomes) instantaneously and irreversibly adhered to the collagen surface in the presence of soluble von Willebrand factor (VWF) at high shear rates, in marked contrast with translocation of liposomes carrying rGPIb alone on the VWF surface. In the absence of soluble VWF, the adhesion of rGPIa/I...

Punching shear-reinforced flat slabs can fail in three modes: (1) inside the zone, (2) outside or (3) at maximum punching shear capacity. By using theory of structural systems reliability, this study investigates how these failure modes combined affect safety level reinforced concrete with reinforcement, and ultimately, variation partial factors. Based on DIN EN 1992-1-1 together German Nationa...