Direct oxygen partial pressure (pO2) readings in cancers of the cervix and in the normal cervix of nulliparous or parous women were obtained using a computerized pO2 histography system. The oxygenation status of the tumors was evaluated as a function of clinical staging and histological grading. pO2 measurements were performed with a customized electrode system in conscious pre- and postmenopau...

Several studies have reported increased mortality risk with early natural menopause. More recently, mortality risk was reported to be reduced among women who gave birth at age > or =40 years. The association between reproductive history and mortality was explored among 826 women in a prospective study involving 18,959 person-years of follow-up (from age 50 to 1990-1991) and 108 deaths. After ad...

BACKGROUND: Birth weight- and gestational age-specific perinatal mortality curves intersect when compared across categories of maternal smoking, plurality, race and other factors. No simple explanation exists for this paradoxical observation. METHODS: We used data on all live births, stillbirths and infant deaths in Canada (1991-1997) to compare perinatal mortality rates among singleton and twi...

Using a preclinical model, we investigated whether excess estradiol (E2) or leptin during pregnancy affects maternal mammary tumorigenesis in rats initiated by administering carcinogen 7,12-dimethylbenz(a)anthracene (DMBA) on day 50. Two weeks later, rats were mated, and pregnant dams were treated daily with 10 μg of 17β-estradiol, 15 μg of leptin, or vehicle from gestation day 8 to 19. Tumor d...

There is a need for long-acting birth control methods. Copper-bearing intrauterine contraceptive devices do not have systemic side effects and they are appropriate for parous women who have no excess menstrual flow or cramps at baseline and who have low risk for sexually transmitted infections. Levonorgestrel-releasing intrauterine systems release levonorgestrel directly into uterine cavity. Th...

Granulomatous lobular mastitis (GLM) is a rare and benign condition of unknown etiology, which has been described recently. It primary affects young parous women and usually presents with a unilateral and extra-areolar breast mass. The condition may clinically mimic breast cancer, sometimes leading to misdiagnosis resulting in unnecessary breast surgery.We report two ca...

Data on the return of fertility after discontinuing various methods of contraception were collected from among the women taking part in the Oxford-Family Planning Association contraceptive study. Return of fertility was measured as the time taken to give birth to a child. The fertility of both nulligravid and parous women who stopped taking oral contraceptives was initially impaired in comparis...

Of 17 032 women taking part in the Oxford Family Planning Association contraceptive study, 4104 stopped using a birth control method to plan a pregnancy on a total of 6199 occasions. The influence of various factors on fertility in these women was assessed by measuring the time taken to give birth to a child. An appreciable inverse relation was observed between age at stopping contraception and...

Introduction: Pelvic organ prolapse is a common condition that occurs in parous women and affects the quality of life of women. The present study aimed to evaluate the incidence of recurrent prolapse. Materials and methods: In a cross-sectional study evaluated 365 women attending two public centers of Ilam, West of Iran. Sampling was done by the simple random sampling method. All women parti...