background: sandhoff disease is an autosomal recessive disorder caused by β-hexosaminidase deficiency and accumulation of gm2 ganglioside resulting in progressive motor neuron manifestations and death from respiratory failure and infections in infantiles. pathogenic mutations in hexb gene were observed which leads to enzyme activity reduction and interruption of normal metabolic cycle of gm2 ga...

background and objective: staphylococcus aureus is an important infection in hemodialysis patients. we studied the prevalence of nasal carriage of methicillin-resistant staphylococcus aureus (mrsa) and its antibiotic resistance pattern in patients receiving hemodialysis as well as in dialysis unit staff. materials and methods: from june to september 2012, we evaluated 74 cases including 61 pati...

introduction: depression is one of the most prevalent mental disorders in patients with diabetes, which affects on cooperation in implementation of treatment measures, consequences of therapeutic and diabetes complications. is thought, low self-esteem is endangering balance of mental and emotional person and is caused development of depression. this study was performing with goal of comparison ...

background the hepatitis delta virus (hdv) was first discovered by rizzetto in 1977 in a patient with chronic hepatitis b virus (hbv) infection. in 1980, it was shown that hdv was an infectious agent responsible for exacerbation of liver disease in patients with hepatitis. objectives the aim of this study was to determine the seroreactivity of, and to molecularly detect, hdv among hemodialysis ...

background: species of microsporidia have been known as opportunistic obli-gate intracellular parasites particularly in immunocompromised patients. enterocyto-zoon bieneusi is one of most prevalent intestinal microsporida parasites in hiv + /aids patients. in this study, intestinal microsporidia infection was deter-mined in hiv + /aids patients using microscopic and molecular methods. methods: ...

introduction: sulfur mustard (sm), a toxic alkylating gas, can cause serious long-term pulmonary complications such as chronic obstructive pulmonary disease (copd). metabolic syndrome (mets) is one of the important comorbidities of copd. this study was designed to evaluate the frequency of metabolic syndrome in iranian chemical warfare patients (cwps) with copd. materials and methods: thirty cw...

introduction: quality of life is defined as the sense of well-being and satisfaction with daily performances influenced by dental and oral conditions. oral diseases are very common and have impacts on different aspects of individual's life and can change their performances. in other word, they can change the quality of life. the real impact of health and disease on daily performances is conside...

aim and background: this research aimed to compare marital satisfaction between patients with coronary disease and the general population. methods and materials: this case-control study included 50 patients with coronary disease from motahari hospital (fuladshahr, iran) and 50 healthy persons from fuladshahr (iran). the two groups were matched regarding marital status and gender. convenience sa...

background: adverse cutaneous drug reactions (acdrs) are the most commonly reported adverse drug events. the causative drugs and clinical patterns of acdrs are different in various populations. this study was conducted to identify the clinical patterns, causative drugs and reasons for drug administration in patients hospitalized due to acdr. materials and methods: this retrospective study was c...

background: pain is a common experience among mechanically ventilated patients. pain among mechanically ventilated patients is aggravated by factors such as stage of illness, invasive procedures, and surgical interventions. the aim to this study was to investigate pain levels and predictors among mechanically ventilated patients during rest and routine nursing interventions. materials and metho...