dear editor-in-chief   pilomatrixoma is a benign tumor of hair follicle first described as calcifying epithelium (1). it accounts for 1% of all the benign skin tumors (2). it is a slow-growing, firm, dermal or subcutaneous neoplasm, usually measuring fewer than 3 cm in diameter. pilomatricomas are considered benign; rarely recur after surgical excision (3). however, cases of pilomatrixoma with ...

Non-Hodgkin’s lymphomas constitute 25 to 40% of all lymphomas. The gastrointestinal tract is the most common site followed by the head and neck area. Salivary gland involvement is a very rare entity and is involved in 0.5 to 5% of all cases. Among all the major salivary glands, the parotid gland is commonly involved followed by the submandibular glands. Misdiagnosis often leads to unnecessary d...

Parotid gland tumours are rare in dogs. In this report, a 7-year-old, female, spayed bearded collie was presented for subacute onset of neurological signs. A meningoencephalitis unknown origin affecting the cerebellum diagnosed 10 months before had successfully been treated with prednisolone and mycophenolate mofetil. Head CT MRI showed right-sided retropharyngeal mass invading caudal fossa com...

Our immunohistochemical study shows that atrial natriuretic peptide (ANP) is present in both human fetal and adult parotid gland. In the fetuses ANP is localized in cell clusters, while in adult parotid gland, the ANP is seen only in the wall of intra- and extralobular ducts. The results suggest that ANP might play a role in the differentiation of the parotid gland similarly as in brain and tha...

Salivary gland neoplasms are a rare group of tumors; the annual incidence rate is 1 in 100,000 individual, comprising about 3% of all head and neck neoplasms [4]. The mean age of patients with salivary gland tumors is 45 years, peaking in the sixth and seventh decades of life. Benign salivary gland tumors occur more frequently in females, while malignant tumors are slightly more frequent in mal...

Lupus erythematosus (LE) can cause various cutaneous lesions including panniculitis (LE profundus), but salivary gland involvement has been extremely rare in patients with LE. Herein, we report the first documented case of systemic LE with prominent mucoid degeneration and lymphoplasmacytic infiltration in the parotid gland. A 38-year-old Japanese male with histories of autoimmune hemolytic ane...

Pleomorphic adenoma (PA) is the most common benign tumor of salivary glands. Most PAs occur in the parotid (80%), followed by the submandibular gland (10%) and minor salivary and sublingual glands (10%). Submandibular gland PAs usually manifest in the submandibular area as a painless hard mass. Although several recurrent parotid gland PA cases have been reported in the literature, recurrent sub...

Deoxyribonucleic acid (DNA) was extracted from parotid gland tumors with phenol. The injection of this DNA into 24-hour to 1-week-old AKR mice resulted in a 65 per cent incidence of parotid tumors and/or epithelioid thymomas. Oncogenic properties of the DNA preparation were abolished by incubation with deoxyribonuclease. Cell-free filtrates of the parotid tumors inoculated into suckling AKR mic...

UNLABELLED Parotid gland parenchyma histology may be altered by local or systemic, pathological or nonpathological conditions. OBJECTIVE This paper aims to highlight the fatty degeneration of the parotid gland, a not well-known non-pathological condition. METHOD In a retrospective study, we collected a series of 6 patients which presented a swelling of the parotid, but even after extensive ...