AIMS AND BACKGROUND Hepatobiliary cystadenoma and cystadenocarcinoma are rare cystic lesions of the liver. The aim of the study was to discuss the clinical features, diagnostic methods and surgical treatment of hepatobiliary cystadenoma and cystadenocarcinoma in our hospital. METHODS Six patients with hepatobiliary cystadenomas and four with hepatobiliary cystadenocarcinomas were evaluated. W...

NF-κB signaling promotes cancer progression in a large number of malignancies. Metadherin, a coactivator of the NF-κB transcription complex, was recently identified to regulate different signaling pathways that are closely related to cancer. We assessed the immunohistochemical expression of p50, p65, and metadherin in 30 ovarian carcinomas, 15 borderline ovarian tumours, and 31 benign ovarian c...

In an effort to define the pathogenic relationship between ovarian neoplasms spanning the clinicopathological spectrum from benign to malignant, the incidence of Ki-ras and p53 mutations was determined in 20 ovarian cystadenomas, 20 low malignant potential (LMP) tumors of the ovary, and 23 ovarian carcinomas. Using DNA extracted from paraffin embedded tissue, polymerase chain reaction amplifica...

Inhibin production has been demonstrated in malignant epithelial ovarian tumours, but secretion of inhibins by benign cystadenoma has not yet been reported. The present study evaluated the concentrations of inhibin A and inhibin B and the relationship with oestradiol and nitric oxide metabolites in fluid collected from benign ovarian serous cystadenomas (n = 15). In addition, follicular fluid s...

Von Hippel-Lindau syndrome is an autosomal dominant disorder that includes susceptibility to hemangioblastomas of the eyes and central nervous system, renal clear cell carcinoma, multiple pancreatic cysts, serous cystadenomas and pancreatic neuroendocrine tumors, pheochromocytoma, endolymphatic sac tumors, and cystadenomas of the epididymis and broad ligament. We present a 16-year-old male who ...

BACKGROUND The optimal course of clinical follow-up after a diagnosis of breast papillary lesion on a core needle biopsy (CNB) remains elusive. In particular, no reports in literature have addressed this question in African-American population. We describe our experience with breast papillary lesions in a primarily African-American population. METHODS A search of our database for breast papil...

Apocrine hidrocystomas (cystadenomas) are cystic cutaneous neoplasms derived from apocrine sweat glands (1, 2), and they most often present in adults as solitary (rarely multiple) lesions involving the head, eyelids and neck (3). They are also reported infrequently in the apocrine gland bearing areas like axillae, areola of the nipple, periumbilical, anal, and genital areas (3, 4). We present a...

UNLABELLED Mucinous cystadenomas are relatively uncommon benign cystic tumors. Most of them are found in the ovary, pancreas, and appendix. Primary mucinous cystadenoma of spleen is extremely rare and only countable cases have been recorded. These are assumed to arise from heterotopic pancreatic tissue or invaginated spleenic capsular mesothelium. We present a rare case of primary mucinous cyst...

Biliary cystadenomas with ovarian like mesenchymal stroma are rare benign cystic neoplasms of liver which have premalignant potential. A 58-year-old woman presented for the evaluation of a 3.6 cm cyst compressing the hepatic duct, jaundice and abnormal liver enzymes. Endoscopic retrograde cholangiopancreatography (ERCP) and stent placement provided symptomatic improvement. The patient was succe...