Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...

G protein-coupled receptor (GPCR) cascades rely on membrane protein diffusion for signaling and are generally found in spatially constrained subcellular microcompartments. How the geometry of these microcompartments impacts cascade activities, however, is not understood, primarily because of the inability of current live cell-imaging technologies to resolve these small structures. Here, we exam...

Acinetobacter species are emerging as an important nosocomial pathogen. Multidrug-resistant Acinetobacter spp. has limited the option for effective treatment. Although carbapenems are effective for the treatment of such infections, resistance to this drug has recently been reported. This study was undertaken to assess resistance to carbapenem in clinical isolates of Acinetobacter spp. from hosp...

We investigate empirically how the Japanese patent system has affected postwar growth in Japanese total factor productivity. The system has been criticized for several reasons, including that it encourages numerous filings of narrow claims that build incrementally on fundamental technologies developed by domestic and foreign inventors. Stated in different terms, the system was designed to promo...

A simple method is described for the detection of methicillin-resistant strains of Staphylococcus aureus by a disc-diffusion test on 5% NaCl agar. Information is given about the incidence of these strains in the Plymouth area.

Background: In recent years, drug resistance to human pathogenic fungi has been increased. Medicinal plants are one way to overcome antibiotic resistance. The aim of this study was to evaluate the antifungal and inhibitory activity of five medicinal plants on the growth of Candida albicans. Methods: This study was done in the Microbiology Lab of Shahid Bahonar University of Kerman, Iran in 2...