Case report: We report the case of a 45-year-old female patient with myasthenia gravis, who developed reversible signs of pancreatic damage, probably related to immunoglobulin vein infusion therapy (IGiv). During this treatment, the patients had an increase of the serum pancreatic enzymes, greater than five times the upper limit of normal values, resolved, without treatment, after the suspensio...

Pancreatic panniculitis is a rare pathological condition affecting 2-3% of patients with pancreatic disease. In 40% of cases the condition precedes manifestations of pancreatic disease. We report the case of a 71-year-old female who presented with an erythematous tender node which had appeared one month previously, progressing to ulceration and yellowish exudation. No abdominal symptoms. Biopsy...

he phrase “location, location, location” has been Tused in the real estate business for more than 90 years to convey the overriding importance of location in determining value, function, and opportunity. It now may be important in how we approach pancreatitis. Pancreatitis is a painful and often debilitating disease for which there are no specific or effective treatments. Although patient morta...

Protein microarrays are playing an increasingly important role in the discovery and characterization of protein-ligand interactions. The uniform orientation conferred by site-specific immobilization is a demonstrable advantage in using such microarrays. Here, we report on a general strategy for fabricating gold surfaces displaying a protein in a uniform orientation. An azido group was installed...

It is well known that type 2 diabetes an endocrine disease. Among glucose-lowering medications, α glucosidase which a membrane bound enzyme at the epithelium of small intestine catalyses cleavage glucose from disaccharide are effective for delaying absorption. i.e., inhibitors delay absorption ingested carbohydrates, reducing postprandial glucose. Pancreatic α-amylase key in digestive system an...

Sjögren's syndrome (SS) is an autoimmune disorder affecting primarily the exocrine glands, leading to keratoconjunctivitis sicca (KCS) and xerostomia, but that can also include extraglandular features(1). Due the anatomical, physiological and pathological similarity between the pancreas and the salivary glands, it has been described that the pancreas it is not exempt from the damage produced by...

The pancreatic exocrine secretory response to different combinations of the pancreozymin-like peptide caerulein and secretin was studied in 110 healthy control subjects and 32 patients with pancreatic disease. A combination of 0 5 CU/kg-h secretin and 75 ng/kg-h caerulein provided maximal or near-maximal stimulation of the secretion of both bicarbonate and pancreatic enzymes. The combination of...