Chen, L. 2017. Molecular Tools for Biomarker Detection. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1387. 48 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0114-3. The advance of biological research promotes the emerging of new methods and solutions to answer the biological questions. This thesis describes several new molecular tools and t...

A fiber coating from polyaniline (PANI) was electrochemically prepared and employed for Solid phase micreoextraction (SPME). The PANI film was directly electrodeposited on the platinum wire surface using cyclic voltametry (CV) technique. The same method was applied for the preparation of SPME fiber coated by polyaniline multiwalled carbon nanotubes (PANI/MWCNTs) composite. The concentration of ...

background: cytogenetic analysis, y-chromosome microdeletion screening, fish techniques and other genetic methods have helped in finding the causes of infertility in azoospermic or severe oligoazoospermic cases in the last decade. objective: in the present study, we characterized an abnormal y-chromosome, detected as a mosaic in an azoospermic male ascertained for infertility. materials and met...

background and objectives: pseudomonas aeruginosa is one of the most important opportunistic pathogens in patients who suffer from immunodeficiency and burns. wound infections caused by p. aeruginosa can rapidly change to systemic and life threatening situation. the aim of this study was to apply florescent in situ hybridization (fish) method for rapid detection of p. aeruginosa in burrn patien...

Gliomas are histologically and genetically heterogeneous tumors. However, classical histopathological typing often ignores the high heterogeneity of tumors thus cannot meet requirements precise pathological diagnosis. Here, proximity-anchored in situ spectral coding amplification (ProxISCA) is proposed for multiplexed imaging RNA mutations, enabling visual brain gliomas with different grades at...