نتایج جستجو برای: p16ink4a
تعداد نتایج: 1424 فیلتر نتایج به سال:
Malignant Mesothelioma (MM) is a rare and aggressive form of tumour that affects the lining of the internal organs for which current treatments have not been proven to be very effective. P16INK4A tumour suppressor encoding CDKN2A gene is often downregulated in MM. This protein is a cyclin dependent kinase 4 and 6 inhibitor, that normally phosphorylates RB1, which has to be un-phosphorylated in ...
Immunohistochemical diagnosis and prognosis of small cell lung cancer: the search for new strategies
The aim: to find the optimal combination of immunohistochemical markers for differential diagnosis and prognosis small cell lung cancer in biopsy samples.
 Materials methods. tumor specimens were divided into 3 groups: 1) 25 samples before treatment; 2) procured from autopsies patients, who underwent chemotherapy; 3) 15 other tumors histologically similar SCLC. All formalin fixed paraffin ...
rare and benign epithelial lesion occurring typically in adults aged 50 and over [1]. We report three children under 15 years who presented a single esophageal papilloma. For each patient, the lesion was asymptomatic, the patient had no history of gastroesophageal reflux (GER) or esophagitis, and the lesion was an incidental finding at esophagogastroduodenoscopy. The lesion appeared as a small ...
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