BACKGROUND AND AIMS Periodontitis is a chronic inflammation that involves nitro-oxidative stress with damaging periodontal structural effects. We aimed to evaluate the consequences of low-dose cimetidine on nitro-oxidative stress in periodontitis. METHODS A rat model of ligature-induced periodontitis was used. After two weeks, the periodontitis groups were treated with cimetidine, aminoguanid...

The title compound, [Na(C12H8N2O8P)], consists of one Na(+) cation and one bis-(p-nitro-phen-yl)phosphate anion with a considerable distortion of the phosphate tetra-hedron due to the presence of two P-O ester bonds. The anion bridges five Na(+) cations whereby each cation is chelated by the nitro O atoms of one anion and bonded via a nitro O atom and phosphate O atoms to four other anions. Thi...

Objectives-To clarify the relation between the genetic polymorphism of ALDH2 (low Km aldehyde dehydrogenase) and toluene metabolism. Methods-The study subjects were 253 toluene workers (192 men and 61 women with an age range of 18-66). The genotypes ofALDH2 were classified by artificial restriction fragment length polymorphism into the homozygous genotype of normal ALDH2 (NN), the homozygous ge...

background: ototoxic chemicals can impair the sense of hearing and balance. in the past decades, the ototoxicity of solvents and their interaction with noise have become evident. this study has been carried out in the shoe manufacturing factory in tehran (iran) with the aim of evaluating the combined effects of noise and toluene on the workers' hearing. materials and methods: this cross-se...